Recombinant Human Adenylosuccinate Lyase , His-tagged
Cat.No. : | ADSL-1526H |
Product Overview : | Recombinant human ADSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ADSL-1526H |
Description : | Adenylosuccinate lyase, also known as ADSL, is an enzyme that converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle. Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency). ADSL deficiency is an autosomal recessive disorder characterized by the accumulation in the body fluids of succinylaminoimidazole-carboxamide riboside (SAICA-riboside) and succinyladenosine (S-Ado). Recombinant human ADSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Molecular Weight : | 59kDa (520aa) |
Form : | Liquid. In 20mM Tris-HCl buffer (PH 8.0) containing 1mM DTT, 40% glycerol, 0.1 mM NaCl |
Purity : | > 95% by SDS - PAGE |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAAG GDHGSPDSYR SPLASRYASP EMCFVFSDRY KFRTWRQLWL WLAEAEQTLG LPITDEQIQE MKSNLENIDF KMAAEEEKRL RHDVMAHVHT FGHCCPKAAG IIHLGATSCY VGDNTDLIIL RNALDLLLPK LARVISRLAD FAKERASLPT LGFTHFQPAQ LTTVGKRCCL WIQDLCMDLQ NLKRVRDDLR FRGVKGTTGT QASFLQLFEG DDHKVEQLDK MVTEKAGFKR AFIITGQTYT RKVDIEVLSV LASLGASVHK ICTDIRLLAN LKEMEEPFEK QQIGSSAMPY KRNPMRSERC CSLARHLMTL VMDPLQTASV QWFERTLDDS ANRRICLAEA FLTADTILNT LQNISEGLVV YPKVIERRIR QELPFMATEN IIMAMVKAGG SRQDCHEKIR VLSQQAASVV KQEGGDNDLI ERIQVDAYFS PIHSQLDHLL DPSSFTGRAS QQVQRFLEEE VYPLLKPYES VMKVKAELCL |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | ADSL Adenyiosuccinate Lyase [ Homo sapiens ] |
Official Symbol : | ADSL |
Synonyms : | ADSL; adenylosuccinate lyase; adenylosuccinase; ASL; AMPS; ASASE; ASase; Adenylosuccinase; EC4.3.2; EC4.3.2.2; OTTHUMP0000199172; OTTHUMP0000199173 |
Gene ID : | 158 |
mRNA Refseq : | NM_000026 |
Protein Refseq : | NP_000017 |
MIM : | 60822 |
UniProt ID : | P30566 |
Chromosome Location : | 22q13.1 |
Function : | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; NOT N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; lyase activity |
Products Types
◆ Recombinant Protein | ||
Adsl-549M | Recombinant Mouse Adsl Protein, MYC/DDK-tagged | +Inquiry |
ADSL-0288H | Recombinant Human ADSL Protein (M1-L484), Tag Free | +Inquiry |
ADSL-90H | Recombinant Human ADSL Protein, His-tagged | +Inquiry |
ADSL-369M | Recombinant Mouse ADSL Protein, His (Fc)-Avi-tagged | +Inquiry |
ADSL-0289H | Recombinant Human ADSL Protein (M1-L484), His/Strep tagged | +Inquiry |
◆ Lysates | ||
ADSL-8995HCL | Recombinant Human ADSL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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