Recombinant Human ADH1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ADH1A-3601H
• Product Overview: ADH1A MS Standard C13 and N15-labeled recombinant protein (NP_000658) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.7 kDa
• AA Sequence: MSTAGKVIKCKAAVLWELKKPFSIE EVEVAPPKAHEVRIKMVAAGICRSD EHVVSGNLVTPLPVILGHEAAGIVE SVGEGVTTVKPGDKVIPLFTPQCGK CRICKNPESNYCLKNDLGNPRGTLQ DGTRRFTCSGKPIHHFVGVSTFSQY TVVDENAVAKIDAASPLEKVCLIGC GFSTGYGSAVKVAKVTPGSTCAVFG LGGVGLSVVMGCKAAGAARIIAVDI NKDKFAKAKELGATECINPQDYKKP IQEVLKEMTDGGVDFSFEVIGRLDT MMASLLCCHEACGTSVIVGVPPDSQ NLSINPMLLLTGRTWKGAIFGGFKS KESVPKLVADFMAKKFSLDALITNI LPFEKINEGFDLLRSGKSIRTILMF TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide [ Homo sapiens (human) ]
• Official Symbol: ADH1A
• Synonyms: ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide; ADH1; alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide
• Gene ID: 124
• mRNA Refseq: NM_000667
• Protein Refseq: NP_000658
• MIM: 103700
• UniProt ID: P07327