Recombinant Human ADH5 cell lysate
Cat.No. : | ADH5-30HCL |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide [ Homo sapiens ] |
Official Symbol : | ADH5 |
Synonyms : | ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide; FDH, formaldehyde dehydrogenase; alcohol dehydrogenase class-3; ADH 3; ADHX; formaldehyde dehydrogenase; alcohol dehydrogenase class-III; alcohol dehydrogenase class chi chain; S-(hydroxymethyl)glutathione dehydrogenase; glutathione-dependent formaldehyde dehydrogenase; alcohol dehydrogenase (class III), chi polypeptide; FDH; ADH-3; FALDH; GSNOR; GSH-FDH; |
Gene ID : | 128 |
mRNA Refseq : | NM_000671 |
Protein Refseq : | NP_000662 |
MIM : | 103710 |
UniProt ID : | P11766 |
Chromosome Location : | 4q23 |
Pathway : | Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD) activity; electron carrier activity; fatty acid binding; formaldehyde dehydrogenase activity; metal ion binding; nucleotide binding; oxidoreductase activity; protein homodimerization activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
Adh5-543M | Recombinant Mouse Adh5 Protein, MYC/DDK-tagged | +Inquiry |
ADH5-284H | Recombinant Human ADH5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADH5-0257H | Recombinant Human ADH5 Protein (M1-I374), GST tagged | +Inquiry |
ADH5-180R | Recombinant Rat ADH5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADH5-344M | Recombinant Mouse ADH5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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