Recombinant Human ADRM1/UCH37 Protein

• Cat.No.: ADRM1/UCH37-309H
• Product Overview: Recombinant Human ADRM1/UCH37 Protein is produced by Bacteria expression system.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Adrm1 is an integral Ub receptor of the 26S proteasome. Adrm1 binds both Ub and polyUb chains via its N-terminal Pru domain. The Pru domain also binds S1 to locate Adrm1 on the 26S proteasome. The C-terminal domain of Adrm1 binds and activates the deubiquitinating enzyme Uch37, though which Uch37 is recruited to the 26S proteasome. Currently, it is not known whether Adrm1 activates Uch37 to deubiquitinate polyUb chains.
• Form: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
• Molecular Mass: ADRM1 (42,2 kDa) & UCH37 (37.6 kDa)
• Purity: > 95 % by SDS-PAGE
• Storage: Store at -80 centigrade; avoid multiple freeze-thaw cycles.

Gene Information

• Gene Name: ADRM1 adhesion regulating molecule 1 ( Homo sapiens (human) ) & UCHL5 ubiquitin C-terminal hydrolase L5 ( Homo sapiens (human) )
• Official Symbol: ADRM1 & UCHL5
• Synonyms: ADRM1 (Adrm1; ARM1; GP110; Rpn13 ) & UCH37 (UCHL5; Uch37; CGI-70; INO80R; UCH-L5 )
• Gene ID: 11047 & 51377
• mRNA Refseq: NM_007002 & NM_015984
• Protein Refseq: NP_008933 & NP_057068
• UniProt ID: Q16186 & Q9Y5K5