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Recombinant Human AFAP1 Protein, His-tagged

Cat.No. : AFAP1-543H
Product Overview : Recombinant Human AFAP1, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.
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Description : The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 80.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : AFAP1 actin filament associated protein 1 [ Homo sapiens ]
Official Symbol : AFAP1
Synonyms : AFAP1; actin filament associated protein 1; actin filament-associated protein 1; AFAP; AFAP 110; 110 kDa actin filament-associated protein; actin filament-associated protein, 110 kDa; AFAP110; AFAP-110; FLJ56849;
Gene ID : 60312
mRNA Refseq : NM_198595
Protein Refseq : NP_940997
MIM : 608252
UniProt ID : Q8N556

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does AFAP1 protein contribute to disease development or pathophysiological conditions, and what are the underlying molecular mechanisms? 02/03/2023

AFAP1 protein contributes to disease development or pathophysiological conditions, and the underlying molecular mechanisms are currently being investigated.

How does dysregulation or dysfunction of AFAP1 protein affect cellular homeostasis, molecular signaling networks, or disease progression? 12/17/2022

Dysregulation or dysfunction of AFAP1 protein can disrupt cellular homeostasis, perturb molecular signaling networks, and contribute to disease progression.

Can AFAP1 protein be targeted or manipulated to modulate cellular processes, and what are the potential therapeutic implications? 02/26/2022

AFAP1 protein holds potential as a target for modulating cellular processes, and further research is needed to explore its therapeutic implications and potential interventions.

Does AFAP1 protein interact with specific molecules or form protein complexes, and what are the functional implications of these interactions? 02/24/2021

AFAP1 protein interacts with specific molecules or forms protein complexes, which have functional implications in various cellular processes.

What is the role of AFAP1 protein in cellular processes, such as cytoskeletal dynamics, cell migration, or signal transduction, and how can its function be investigated experimentally? 03/03/2020

AFAP1 protein plays a role in cellular processes such as cytoskeletal dynamics, cell migration, or signal transduction, and its function can be investigated experimentally using techniques like siRNA knockdown or overexpression studies.

What is the subcellular localization of AFAP1 protein, and how can it be experimentally determined? 01/28/2019

The subcellular localization of AFAP1 protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.

What experimental techniques or assays have been used to study the functional significance of AFAP1 protein, such as co-immunoprecipitation, live-cell imaging, or functional assays? 05/17/2016

Various experimental techniques or assays, such as co-immunoprecipitation, live-cell imaging, or functional assays, have been used to study the functional significance of AFAP1 protein.

Are there any known post-translational modifications or regulatory mechanisms that modulate the activity or stability of AFAP1 protein? 06/09/2015

Post-translational modifications and regulatory mechanisms modulate the activity or stability of AFAP1 protein.

Are there any genetic variations or mutations in the gene encoding AFAP1 protein that impact its expression or function, and what are the consequences for cellular processes or disease susceptibility? 02/03/2015

Genetic variations or mutations in the gene encoding AFAP1 protein may impact its expression or function, influencing cellular processes or disease susceptibility.

How is the expression of AFAP1 protein regulated, and what factors or signaling pathways are involved in its expression control? 01/16/2015

The expression of AFAP1 protein is regulated, and specific factors or signaling pathways are involved in its expression control.

Customer Reviews (3)

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Reviews
03/18/2022

    Unraveling protein-protein interactions in RNA processing for gene expression control.

    03/02/2019

      Mapping protein-protein interactions in DNA transcription for gene regulation.

      11/09/2018

        Investigating protein-protein interactions in autophagy pathways for cellular homeostasis.

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