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Recombinant Human AFMID Protein, His-tagged

Cat.No. : AFMID-316H
Product Overview : Recombinant Human AFMID, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Tag : His
Form : 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Mass : 33.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : AFMID arylformamidase [ Homo sapiens ]
Official Symbol : AFMID
Synonyms : KF
Gene ID : 125061
mRNA Refseq : NM_001145526.2
Protein Refseq : NP_001138998.1
UniProt ID : Q63HM1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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How does dysregulation or dysfunction of AFMID protein contribute to human diseases, and what experimental models or techniques can be employed to study these associations? 01/12/2023

Dysregulation or dysfunction of AFMID protein is implicated in human diseases, and associations can be investigated using disease models, patient samples, or genetically modified systems, combined with phenotypic assessments or molecular analysis techniques.

What is the enzymatic activity of AFMID protein, and how can it be experimentally measured or characterized? 02/20/2022

The enzymatic activity of AFMID protein can be measured or characterized using biochemical assays or enzymatic activity assays specific to its function.

What is the enzymatic activity of AMDHD1 and its substrate specificity? 02/01/2022

AMDHD1 possesses enzymatic activity, such as hydrolase or esterase activity, and exhibits specificity towards specific lipid substrates.

Can AFMID protein be targeted or modulated to manipulate specific metabolic pathways or alleviate disease conditions, and what experimental strategies can be used to evaluate its therapeutic potential? 01/14/2022

AFMID protein can be targeted or modulated to manipulate specific metabolic pathways or alleviate disease conditions, and its therapeutic potential can be evaluated using in vitro or in vivo models, combined with functional assays or disease outcome measures.

Can targeting AMDHD1 activity or expression provide potential therapeutic strategies for metabolic disorders or other related diseases? 09/27/2021

Modulating AMDHD1 activity or expression may hold therapeutic potential for metabolic disorders, providing opportunities for developing interventions that target lipid metabolism or oxidative stress-related pathways.

What are the downstream metabolic pathways or cellular processes influenced by AFMID protein activity, and what experimental approaches can be used to investigate these effects? 07/08/2021

AFMID protein influences downstream metabolic pathways or cellular processes, which can be investigated through metabolomic profiling, genetic or pharmacological perturbations, or functional assays specific to the pathways of interest.

What are the molecular interactions of AMDHD1 with other proteins and their role in cellular processes? 04/20/2021

AMDHD1 interacts with other proteins involved in lipid metabolism, such as enzymes or transporters, and these interactions modulate cellular processes such as lipid synthesis, degradation, or transport.

How is AMDHD1 expression regulated under different physiological conditions or in response to cellular stresses? 03/27/2021

AMDHD1 expression is regulated at transcriptional and post-transcriptional levels, influenced by hormonal signals, nutritional status, or cellular stresses.

What is the tissue-specific expression pattern of AMDHD1 and its potential functional implications? 02/21/2021

AMDHD1 exhibits a tissue-specific expression pattern, with higher levels observed in tissues with active lipid metabolism, suggesting its involvement in lipid-related processes.

What are the structural features of AMDHD1 that are critical for its enzymatic function and protein-protein interactions? 01/23/2021

The enzymatic function and protein interactions of AMDHD1 are dependent on its unique structural features, including catalytic residues and protein interaction domains.

How does AFMID protein participate in cellular redox balance or oxidative stress response, and what experimental approaches can be used to investigate its involvement in these processes? 01/14/2021

AFMID protein participates in cellular redox balance or oxidative stress response, and its involvement in these processes can be investigated using techniques such as redox assays, ROS detection, or genetic manipulations combined with functional assessments.

How does AMDHD1 contribute to lipid metabolism and homeostasis? 11/10/2020

AMDHD1 plays a role in lipid metabolism by participating in the breakdown or remodeling of specific lipid molecules, contributing to lipid homeostasis.

What are the structural features or domains of AFMID protein, and how do they contribute to its enzymatic activity or substrate specificity? 10/26/2020

The structural features or domains of AFMID protein contribute to its enzymatic activity or substrate specificity, and their functional roles can be investigated using techniques such as protein structure determination, site-directed mutagenesis, or biochemical assays.

How is the expression of AFMID protein regulated, and what factors or signaling pathways control its expression levels? 10/10/2020

The expression of AFMID protein is regulated by specific factors and signaling pathways that control its transcriptional or post-transcriptional regulation.

How does AMDHD1 deficiency or overexpression affect cellular physiology and contribute to disease phenotypes? 05/12/2020

AMDHD1 deficiency or dysregulation may lead to altered lipid metabolism, mitochondrial dysfunction, or cellular stress, potentially contributing to metabolic disorders or other related diseases.

Are there any genetic variations or mutations in the gene encoding AFMID protein that impact its expression or function, and what are the implications for disease susceptibility or metabolic disorders? 02/29/2020

Genetic variations or mutations in the gene encoding AFMID protein may impact its expression or function, leading to altered susceptibility to diseases or metabolic disorders, and these can be studied through genetic association studies or functional characterization of mutant variants.

What are the endogenous substrates or metabolites of AFMID protein, and how can their interactions be studied or quantified? 06/10/2018

AFMID protein interacts with endogenous substrates or metabolites, and their interactions can be studied or quantified using techniques such as mass spectrometry, metabolomics analysis, or enzymatic assays.

How does AMDHD1 participate in the regulation of cellular redox balance and oxidative stress response? 06/12/2017

AMDHD1 contributes to maintaining cellular redox balance by participating in lipid metabolism pathways linked to antioxidant defense mechanisms.

What are the downstream signaling pathways or cellular processes influenced by AMDHD1 activity? 04/06/2017

AMDHD1 activity can influence downstream signaling pathways, including those involved in lipid signaling, cellular energy homeostasis, or inflammation.

Are there any known post-translational modifications or regulatory mechanisms that modulate the activity or stability of AFMID protein? 05/07/2015

Post-translational modifications or regulatory mechanisms may modulate the activity or stability of AFMID protein, and these can be studied using techniques such as site-directed mutagenesis, phosphoproteomics analysis, or biochemical assays.

Customer Reviews (3)

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Reviews
10/19/2021

    Unraveling protein-protein interactions in lipid metabolism for metabolic disorders.

    12/29/2017

      Elucidating protein-protein interactions in cell adhesion for tissue morphogenesis.

      07/10/2017

        Exploring protein-protein interactions in neurodegenerative diseases for therapeutic targets.

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