Active Recombinant Human AGER Protein
Cat.No. : | AGER-328H |
Product Overview : | Recombinant mature form of human AGER (NP_001127.1) (Met1-Ala 344) was expressed with six amino acids (LEVLFQ) at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Predicted N Terminal : | Ala 23 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | 1. Measured by its ability to compete with Biotinylated recombinant human AGER for binding to immobilized recombinant human Fc-S100B in a functional ELISA.2. Measured by its ability to compete with Biotinylated recombinant human AGER for binding to immob |
Molecular Mass : | The recombinant human AGER consists of 329 amino acids and predicts a molecular mass of 35 KDa. It migrates as an approximately 46-52 KDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | AGER advanced glycosylation end product-specific receptor [ Homo sapiens ] |
Official Symbol : | AGER |
Synonyms : | AGER; advanced glycosylation end product-specific receptor; RAGE; RAGE isoform sRAGE-delta; RAGE isoform NtRAGE-delta; |
Gene ID : | 177 |
mRNA Refseq : | NM_001136 |
Protein Refseq : | NP_001127 |
MIM : | 600214 |
UniProt ID : | Q15109 |
Chromosome Location : | 6p21.3 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem; |
Products Types
◆ Lysates | ||
AGER-1480HCL | Recombinant Human AGER cell lysate | +Inquiry |
AGER-2215MCL | Recombinant Mouse AGER cell lysate | +Inquiry |
AGER-2546HCL | Recombinant Human RAGE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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