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Recombinant Human AGO2 Protein, MYC/DDK-tagged

Cat.No. : AGO2-526H
Product Overview : Recombinant Human AGO2, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 93.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : AGO2 argonaute 2, RISC catalytic component [ Homo sapiens ]
Official Symbol : AGO2
Synonyms : PPD; Q10; CASC7; EIF2C2; LINC00980
Gene ID : 27161
mRNA Refseq : NM_001164623
Protein Refseq : NP_001158095
MIM : 606229
UniProt ID : Q9UKV8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (21)

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How is AGO2’s interaction with target mRNAs studied 12/09/2022

Research explores how AGO2 guides small RNAs to complementary target mRNA sequences.

How is AGO2’s function studied in RNA silencing 11/26/2022

Research explores AGO2’s role in guiding small RNAs to their target sequences.

Can AGO2’s activity be involved in antiviral defense 09/09/2022

Yes, AGO2 is part of the antiviral RNA interference pathway.

Can AGO2 influence gene expression 11/04/2021

Yes, AGO2’s activity leads to the suppression or degradation of target mRNAs.

How is AGO2’s involvement in chromatin remodeling studied 10/26/2021

Research investigates AGO2’s connection to chromatin remodeling complexes.

How does AGO2’s dysfunction relate to diseases 10/29/2020

AGO2 dysfunction is linked to disorders involving impaired gene regulation.

Is AGO2 essential for normal development 02/18/2020

Yes, AGO2 is essential for normal development and cellular processes.

What’s the role of AGO2 in RNA interference 06/10/2019

AGO2 plays a central role in mediating RNA silencing and post-transcriptional regulation.

How does AGO2’s role relate to post-transcriptional regulation 05/11/2019

AGO2 helps control gene expression by degrading or inhibiting mRNA translation.

Can AGO2 influence stem cell maintenance 11/28/2018

Yes, AGO2’s function is important for maintaining stem cell populations.

Is AGO2’s activity modulated during stress responses 09/26/2018

Yes, AGO2’s activity can be regulated in response to cellular stress.

Can AGO2’s function be studied in cancer research 08/09/2018

Yes, AGO2’s role in gene regulation is relevant in cancer studies.

Can AGO2 be involved in epigenetic regulation 07/13/2018

Yes, AGO2’s role extends to epigenetic regulation through RNA-directed DNA methylation.

Can AGO2’s activity affect circadian rhythm regulation 06/01/2018

Yes, AGO2’s function is linked to post-transcriptional regulation of circadian genes.

Can AGO2’s function impact heterochromatin formation 05/19/2018

Yes, AGO2’s activity can influence heterochromatin formation and genome stability.

How does AGO2’s role in translation repression work 06/19/2017

AGO2’s activity leads to translational repression through mRNA cleavage or inhibition.

Can AGO2 impact transposable element silencing 04/19/2017

Yes, AGO2 is involved in suppressing transposable element activity.

How does AGO2 interact with small RNAs 11/29/2016

AGO2 interacts with small RNAs, including microRNAs and small interfering RNAs.

How is AGO2’s role in exosome-mediated RNA decay studied 09/06/2016

Research explores AGO2’s contribution to targeting RNAs for exosome-mediated decay.

How is AGO2’s involvement in germline development studied 05/18/2016

Research investigates AGO2’s role in regulating germline development and fertility.

How does AGO2’s role relate to neuronal function 05/09/2016

AGO2’s activity impacts neuronal development and synaptic plasticity.

Customer Reviews (5)

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Reviews
05/21/2021

    The high purity of the protein product facilitated accurate quantification of target molecules.

    10/08/2020

       Well-defined gel electrophoresis bands were indicative of the protein product’s pure form.

      09/14/2017

         Incorporating the product led to a noticeable increase in target protein expression levels.

        03/11/2017

           Precise results from immunoprecipitation assays were attributed to the protein product’s purity.

          09/12/2016

            Consistency across experiments made the protein product a reliable research tool.

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