Human AGO2 Knockdown Cell Lysate

• Cat.No.: AGO2-029HKCL
• Product Overview: WB-validated AGO2 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 97 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg AGO2 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: AGO2 argonaute RISC catalytic component 2 [ Homo sapiens (human) ]
• Official Symbol: AGO2
• Synonyms: AGO2; argonaute RISC catalytic component 2; PPD; Q10; CASC7; EIF2C2; LESKRES; LINC00980; protein argonaute-2; PAZ Piwi domain protein; argonaute 2, RISC catalytic component; cancer susceptibility candidate 7 (non-protein coding); eukaryotic translation initiation factor 2C, 2; long intergenic non-protein coding RNA 980; protein slicer; EC 3.1.26.n2
• Gene ID: 27161
• mRNA Refseq: NM_012154
• Protein Refseq: NP_036286
• MIM: 606229
• UniProt ID: Q9UKV8