Recombinant Human AHNAK2 Protein, GST-tagged
Cat.No. : | AHNAK2-463H |
Product Overview : | Human AHNAK2 partial ORF ( XP_290629.5, 5527 a.a. - 5636 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a large nucleoprotein. The encoded protein has a tripartite domain structure with a relatively short N-terminus and a long C-terminus, separated by a large body of repeats. The N-terminal PSD-95/Discs-large/ZO-1 (PDZ)-like domain is thought to function in the formation of stable homodimers. The encoded protein may play a role in calcium signaling by associating with calcium channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 37.84 kDa |
AA Sequence : | ELPKKQEKAGWFRFPKLGFSSSPTK KSKSTEDGAELEEQKLQEETITFFD ARESFSPEEKEEGELIGPVGTGLDS RVMVTSAARTELILPEQDRKADDES KGSGLGPNEG |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AHNAK2 AHNAK nucleoprotein 2 [ Homo sapiens ] |
Official Symbol : | AHNAK2 |
Synonyms : | AHNAK2; AHNAK nucleoprotein 2; C14orf78, chromosome 14 open reading frame 78; protein AHNAK2; C14orf78; KIAA2019; |
Gene ID : | 113146 |
mRNA Refseq : | NM_138420 |
Protein Refseq : | NP_612429 |
MIM : | 608570 |
UniProt ID : | Q8IVF2 |
Products Types
◆ Recombinant Protein | ||
AHNAK2-9496H | Recombinant Human AHNAK2, GST-tagged | +Inquiry |
AHNAK2-462H | Recombinant Human AHNAK2 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
AHNAK2-42HCL | Recombinant Human AHNAK2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAHNAK2 expression levels may fluctuate during the cell cycle, with possible implications for cell cycle regulation and progression.
AHNAK2 expression alterations have been observed in certain diseases, but its potential as a diagnostic or prognostic marker requires further clinical validation.
AHNAK2 can undergo phosphorylation and acetylation, which may modulate its interactions with other proteins and its subcellular localization.
AHNAK2 interacts with proteins involved in vesicle transport and organelle dynamics, suggesting its role in intracellular trafficking processes.
AHNAK2 has been implicated in cardiac functions, particularly in the heart's intercalated discs, suggesting a role in maintaining cardiac integrity.
AHNAK2 is recruited to sites of plasma membrane damage and participates in membrane resealing, contributing to cellular membrane repair mechanisms.
Yes, like AHNAK, AHNAK2 can interact with calcium-binding proteins, such as annexins, and influence calcium signaling pathways.
AHNAK2 interacts with components of cell-matrix adhesions and the actin cytoskeleton, playing a role in stabilizing cell adhesion structures and regulating cell migration.
AHNAK2 expression is tightly regulated by various transcription factors and epigenetic modifications, resulting in tissue-specific and cell type-specific expression patterns.
AHNAK2 is involved in various cellular processes, including cell adhesion, membrane repair, calcium signaling, and regulation of the actin cytoskeleton.
Customer Reviews (5)
Write a reviewResearch success made simple with this lab protein.
Our satisfaction with the lab protein product is resounding, and its contribution to our research achievements is profoundly appreciated.
Researchers seeking a reliable and robust lab protein will find this product to be an exemplary addition to their experimental toolkit.
This lab protein deserves a standing ovation – it's fantastic!
The product's user-friendly nature has facilitated seamless integration into our protocols, leading to enhanced experimental outcomes.
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