Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Recombinant Human AHSP Protein, His-tagged

Cat.No. : AHSP-614H
Product Overview : Recombinant Human AHSP(Met1~Ser102) fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 17.6kDa
Identity : Reconstitute in PBS or others
Protein length : Met1~Ser102
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : AHSP alpha hemoglobin stabilizing protein [ Homo sapiens ]
Official Symbol : AHSP
Synonyms : AHSP; alpha hemoglobin stabilizing protein; ERAF, erythroid associated factor; alpha-hemoglobin-stabilizing protein; alpha hemoglobin stabilising protein; EDRF; erythroid associated factor; erythroid-associated factor; erythroid differentiation-related factor; erythroid differentiation associated factor; ERAF;
Gene ID : 51327
mRNA Refseq : NM_016633
Protein Refseq : NP_057717
MIM : 605821
UniProt ID : Q9NZD4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (10)

Ask a question
What techniques are used to quantify the binding affinity between Ahsp and alpha-globin? 04/25/2022

echniques such as isothermal titration calorimetry (ITC) and surface plasmon resonance (SPR) are commonly employed to quantify the binding affinity and kinetics of Ahsp-alpha-globin interactions.

What is the connection between Ahsp and hemoglobinopathies? 01/20/2022

Ahsp deficiency can lead to unstable alpha-globin chains, contributing to the development of certain hemoglobinopathies like alpha-thalassemia.

How does Ahsp respond to cellular stress conditions? 11/17/2021

Ahsp expression may be upregulated during cellular stress to enhance its protective role in stabilizing alpha-globin chains and preventing protein aggregation.

What techniques are commonly used to study the interactions of Ahsp with alpha-globin chains? 03/09/2021

Techniques such as nuclear magnetic resonance (NMR), X-ray crystallography, and molecular dynamics simulations are commonly used to study protein-protein interactions involving Ahsp and alpha-globin.

How does Ahsp interact with chaperone proteins in the cell? 10/31/2020

Ahsp can interact with molecular chaperones like Hsp70 to assist in protein folding and prevent misfolding of alpha-globin chains.

How does Ahsp achieve its stabilizing function at the molecular level? 06/15/2020

Ahsp binds to free alpha-globin chains, preventing their aggregation and degradation by maintaining their folded state.

What is the significance of Ahsp in preventing thalassemia? 09/28/2019

Ahsp plays a role in preventing excess alpha-globin chains from aggregating and precipitating, which is a key factor in the pathogenesis of alpha-thalassemia.

How does Ahsp's function compare to other molecular chaperones in the cell? 07/12/2019

Ahsp's role is unique, focusing specifically on stabilizing alpha-globin chains, whereas other chaperones have broader functions in assisting protein folding and transport.

Can you explain the role of Ahsp in the context of iron metabolism? 12/04/2018

Ahsp indirectly influences iron metabolism by stabilizing alpha-globin chains and preventing their degradation, which in turn maintains balanced globin chain production and minimizes iron waste.

How does Ahsp contribute to maintaining red blood cell stability and lifespan? 09/03/2018

Ahsp's role in stabilizing alpha-globin chains helps prevent the formation of toxic aggregates that could damage red blood cells and shorten their lifespan.

Customer Reviews (5)

Write a review
Reviews
05/13/2022

    Outstanding product supplement. Worth every penny and arrived ahead of schedule.

    03/02/2021

      Top-notch lab protein for a fraction of the cost. Superb value for money.

      07/06/2020

        Great protein quality at an affordable price. Impressed with the results!

        12/27/2019

          Exceptional quality product that doesn't break the bank. Fast delivery too!

          09/18/2018

            This protein product is a game-changer – premium quality and budget-friendly.

            Ask a Question for All AHSP Products

            Required fields are marked with *

            My Review for All AHSP Products

            Required fields are marked with *

            0

            Inquiry Basket

            cartIcon
            logo

            FOLLOW US

            Terms and Conditions        Privacy Policy

            Copyright © 2024 Creative BioMart. All Rights Reserved.

            Contact Us

            • /

            Stay Updated on the Latest Bioscience Trends