Recombinant Human AK7 Protein, GST-tagged
Cat.No. : | AK7-394H |
Product Overview : | Human AK7 full-length ORF ( AAH35256, 1 a.a. - 656 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the adenylate kinase family of enzymes. The encoded enzyme is a phosphotransferase that catalyzes the reversible phosphorylation of adenine nucleotides. This enzyme plays a role in energy homeostasis of the cell. Alternative splicing results in multiple transcript variants. Mutations in the mouse gene are associated with primary ciliary dyskinesia. [provided by RefSeq, Apr 2017] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 97.90 kDa |
AA Sequence : | MAEEEETAALTEKVIRTQRVFINLL DSYSSGNIGKFLSNCVVGASLEEIT EEEEEEDENKSAMLEASSTKVKEGT FQIVGTLSKPDSPRPDFAVETYSAI SREDLLMRLLECDVIIYNITESSQQ MEEAIWAVSALSEEVSHFEKRKLFI LLSTVMTWARSKALDPEDSEVPFTE EDYRRRKSHPNFLDHINAEKMVLKF GKKARKFAAYVVAAGLQYGAEGGML HTFFKMAWLGEIPALPVFGDGTNVI PTIHVLDLAGVIQNVIDHVPKPHYL VAVDESVHTLEDIVKCISKNTGPGK IQKIPRENAYLTKDLTQDCLDHLLV NLRMEALFVKENFNIRWAAQTGFVE NINTILKEYKQSRGLMPIKICILGP PAVGKSSIAKELAKYYKLHHIQLKD VISEAIAKLEAIVAPNDVGEGEEEV EEEEEEENVEDAQELLDGIKESMEQ NAGQLDDQYIIRFMKEKLKSMPCRN RGYILDGFPKTYDQAKDLFNQEDEE EEDDVRGRMFPFDKLIIPEFVCALD ASDEFLKERVINLPESIVAGTHYSQ DRFLRALSNYRDINIDDETVFNYFD ELEIHPIHIDVGKLEDAQNRLAIKQ LIKETGEPRNYGLTDEEKAEGERKA AEERLAREAAEEAEREHQEAVEMAE KIARWE |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AK7 adenylate kinase 7 [ Homo sapiens ] |
Official Symbol : | AK7 |
Synonyms : | AK7; adenylate kinase 7; FLJ32864; putative adenylate kinase 7; |
Gene ID : | 122481 |
mRNA Refseq : | NM_152327 |
Protein Refseq : | NP_689540 |
MIM : | 615364 |
UniProt ID : | Q96M32 |
Products Types
◆ Recombinant Protein | ||
AK7-1236H | Recombinant Human AK7 protein, His&Myc-tagged | +Inquiry |
◆ Lysates | ||
AK7-43HCL | Recombinant Human AK7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (16)
Ask a questionAt present, there is no known direct association between AK7 protein and any specific diseases or disorders. However, as an enzyme involved in cellular energy metabolism, dysregulation of AK7 activity may indirectly contribute to certain metabolic disorders or pathological conditions.
The potential functional consequences of AK7 protein dysregulation are not well understood. However, given its involvement in cellular energy metabolism and nucleotide balance, altered AK7 expression or activity may have implications for cellular ATP production, energy homeostasis, and nucleotide pool levels. Dysregulation of AK7 could potentially disrupt these processes and contribute to cellular dysfunction or disease development, although further research is needed to confirm this.
AK7 protein has been detected in various tissues, including the brain, heart, liver, kidney, and skeletal muscle. Its expression levels may vary across different tissues.
Although the exact roles of AK7 protein in cellular processes are not fully understood, members of the adenylate kinase family, including AK7, are believed to play a role in maintaining energy homeostasis. The transfer of phosphate groups between nucleotides catalyzed by AK7 may contribute to the regulation of cellular energy metabolism and nucleotide pool levels.
There is limited information regarding the specific protein interactions of AK7. However, as a member of the adenylate kinase family, AK7 may interact with various nucleotide-binding proteins or enzymes involved in cellular energy metabolism. Further studies are needed to elucidate the protein-protein interactions of AK7 and determine their functional implications.
AK7 protein indirectly influences ATP production and utilization by participating in the maintenance of nucleotide balance within the cell. By catalyzing the transfer of phosphate groups between ATP, AMP, and ADP, AK7 protein helps regulate the availability of these nucleotides for energy production and utilization.
The specific protein-protein interactions or binding partners of AK7 protein have not been extensively characterized. Further studies, such as co-immunoprecipitation or yeast two-hybrid assays, may shed light on potential interaction partners of AK7 protein.
The therapeutic potential of targeting AK7 protein has not been extensively explored. Given its involvement in cellular energy metabolism, dysregulation of AK7 could potentially contribute to certain diseases. Further investigations are required to evaluate the feasibility and efficacy of targeting AK7 for therapeutic interventions.
The regulation of AK7 protein expression and activity is not well characterized. It is possible that AK7 expression may be regulated at the transcriptional or post-translational level to meet the cellular demands for nucleotide metabolism. More research is needed to understand the regulatory mechanisms controlling AK7 in the cell.
Currently, there is limited information available on genetic polymorphisms or mutations specifically associated with AK7 protein. Further studies, including genetic analyses and population studies, are required to identify potential variants in the AK7 gene and determine their functional significance or associations with diseases.
Limited research has been conducted on AK7 protein, and there is no specific information about its study in model organisms or animal models. Further investigations may utilize model systems to understand the protein's function and relevance.
There is limited information available regarding mutations or genetic variations in AK7 protein. Further research is needed to identify any specific variants that may be associated with human health or disease.
Information regarding specific inhibitors or activators of AK7 protein is scarce. Further research is needed to identify compounds that can modulate AK7 activity and determine their potential therapeutic implications.
There is currently no evidence to suggest that AK7 protein can be used as a diagnostic marker for specific diseases. However, further studies may investigate potential associations between altered AK7 expression or activity and certain diseases or pathologies.
AK7 protein belongs to the adenylate kinase family, which consists of multiple homologs or paralogs with similar enzymatic activities. Some of the known homologs include AK1 (Adenylate Kinase 1), AK2, AK3, and AK6. These homologs may have slightly different tissue distributions and substrate specificities compared to AK7.
AK7 protein is predominantly localized in the cytoplasm of cells. However, its precise subcellular distribution within the cytoplasm and potential organelle associations are not well characterized.
Customer Reviews (4)
Write a reviewAK7 protein is a pinnacle of quality, assuring that it will impeccably fulfill all my experimental requisites.
In addition to the extraordinary quality of the AK7 protein, the manufacturer also offers exceptional technical support that proves instrumental in resolving any challenges I may face.
Their team of knowledgeable experts is renowned for their unwavering commitment to customer satisfaction.
It empowers me to surpass scientific hurdles, unravel mysteries, and establish novel insights, ultimately propelling my research to new heights of innovation and discovery.
Ask a Question for All AK7 Products
Required fields are marked with *
My Review for All AK7 Products
Required fields are marked with *
Inquiry Basket