Recombinant Human AKT3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: AKT3-1566H
• Product Overview: AKT3 MS Standard C13 and N15-labeled recombinant protein (NP_859029) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.9 kDa
• AA Sequence: MSDVTIVKEGWVQKRGEYIKNWRPR YFLLKTDGSFIGYKEKPQDVDLPYP LNNFSVAKCQLMKTERPKPNTFIIR CLQWTTVIERTFHVDTPEEREEWTE AIQAVADRLQRQEEERMNCSPTSQI DNIGEEEMDASTTHHKRKTMNDFDY LKLLGKGTFGKVILVREKASGKYYA MKILKKEVIIAKDEVAHTLTESRVL KNTRHPFLTSLKYSFQTKDRLCFVM EYVNGGELFFHLSRERVFSEDRTRF YGAEIVSALDYLHSGKIVYRDLKLE NLMRDKDGHIKITDFGLCKEGITDA ATMKTFCGTPEYLAPEVLEDNDYGR AVDWWGLGVVMYEMMCGRLPFYNQD HEKLFELILMEDIKFPRTLSSDAKS LLSGLLIKDPNKRLGGGPDDAKEIM RHSFFSGVNWQDVYDKKLVPPFKPQ VTSETDTRYFDEEFTAQTITITPPE KCQQSDCGMLGNWKKTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: AKT3 AKT serine/threonine kinase 3 [ Homo sapiens (human) ]
• Official Symbol: AKT3
• Synonyms: AKT3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); RAC-gamma serine/threonine-protein kinase; PKBG; PRKBG; RAC gamma; PKB gamma; RAC-gamma serine/threonine protein kinase; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma; DKFZp434N0250
• Gene ID: 10000
• mRNA Refseq: NM_181690
• Protein Refseq: NP_859029
• MIM: 611223
• UniProt ID: Q9Y243