Recombinant Human ALDH8A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ALDH8A1-1807H
• Product Overview: ALDH8A1 MS Standard C13 and N15-labeled recombinant protein (NP_072090) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.4 kDa
• AA Sequence: MAGTNALLMLENFIDGKFLPCSSYI DSYDPSTGEVYCRVPNSGKDEIEAA VKAAREAFPSWSSRSPQERSRVLNQ VADLLEQSLEEFAQAESKDQGKTLA LARTMDIPRSVQNFRFFASSSLHHT SECTQMDHLGCMHYTVRAPVGVAGL ISPWNLPLYLLTWKIAPAMAAGNTV IAKPSELTSVTAWMLCKLLDKAGVP PGVVNIVFGTGPRVGEALVSHPEVP LISFTGSQPTAERITQLSAPHCKKL SLELGGKNPAIIFEDANLDECIPAT VRSSFANQGEICLCTSRIFVQKSIY SEFLKRFVEATRKWKVGIPSDPLVS IGALISKAHLEKVRSYVKRALAEGA QIWCGEGVDKLSLPARNQAGYFMLP TVITDIKDESCCMTEEIFGPVTCVV PFDSEEEVIERANNVKYGLAATVWS SNVGRVHRVAKKLQSGLVWTNCWLI RELNLPFGGMKSSGIGREGAKDSYD FFTEIKTITVKHTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ALDH8A1 aldehyde dehydrogenase 8 family member A1 [ Homo sapiens (human) ]
• Official Symbol: ALDH8A1
• Synonyms: ALDH8A1; aldehyde dehydrogenase 8 family, member A1; aldehyde dehydrogenase family 8 member A1; ALDH12; aldehyde dehydrogenase 12; aldehyde dehydrogenase family protein; DJ352A20.2; MGC138650; DKFZp779D2315
• Gene ID: 64577
• mRNA Refseq: NM_022568
• Protein Refseq: NP_072090
• MIM: 606467
• UniProt ID: Q9H2A2