Recombinant Human ALS2 Protein, His-tagged
Cat.No. : | ALS2-166H |
Product Overview : | Recombinant Human ALS2, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 50mM Tris, 8M Urea, pH8.0. |
Molecular Mass : | 42.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ALS2 amyotrophic lateral sclerosis 2 (juvenile) [ Homo sapiens ] |
Official Symbol : | ALS2 |
Synonyms : | ALS2; amyotrophic lateral sclerosis 2 (juvenile); ALS2CR6, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6; alsin; amyotrophic lateral sclerosis 2 protein; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; ALSJ; PLSJ; IAHSP; ALS2CR6; FLJ31851; KIAA1563; MGC87187; |
Gene ID : | 57679 |
mRNA Refseq : | NM_001135745 |
Protein Refseq : | NP_001129217 |
MIM : | 606352 |
UniProt ID : | Q96Q42 |
Products Types
◆ Recombinant Protein | ||
ALS2-491M | Recombinant Mouse ALS2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALS2-298R | Recombinant Rat ALS2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Als2-3402R | Recombinant Rat Als2, His-tagged | +Inquiry |
ALS2-497H | Recombinant Human ALS2 Protein, GST-tagged | +Inquiry |
ALS2-642R | Recombinant Rat ALS2 Protein | +Inquiry |
◆ Lysates | ||
ALS2-66HCL | Recombinant Human ALS2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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