Recombinant Human AMACR, His-tagged
Cat.No. : | AMACR-107H |
Product Overview : | Recombinant Human AMACR, transcript variant 2, fused with N-terminal HIS, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 22 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Gene Name : | AMACR alpha-methylacyl-CoA racemase [ Homo sapiens (human) ] |
Official Symbol : | AMACR |
Synonyms : | AMACR; RM; RACE; CBAS4; AMACRD; alpha-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; NP_001161067.1; EC 5.1.99.4; NP_055139.4; NP_976316.1 |
Gene ID : | 23600 |
mRNA Refseq : | NM_203382 |
Protein Refseq : | NP_976316 |
MIM : | 604489 |
UniProt ID : | Q9UHK6 |
Chromosome Location : | 5p13 |
Pathway : | Beta-oxidation of pristanoyl-CoA; Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate; Peroxisomal lipid metabolism |
Function : | alpha-methylacyl-CoA racemase activity; receptor binding |
Products Types
◆ Recombinant Protein | ||
AMACR-140R | Recombinant Rhesus Macaque AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
AMACR-330H | Recombinant Human AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
Amacr-1607M | Recombinant Mouse Amacr Protein, Myc/DDK-tagged | +Inquiry |
AMACR-497M | Recombinant Mouse AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
AMACR-312R | Recombinant Rhesus monkey AMACR Protein, His-tagged | +Inquiry |
◆ Lysates | ||
AMACR-8888HCL | Recombinant Human AMACR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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