Recombinant Human AMACR protein, GST-tagged

• Cat.No.: AMACR-513H
• Product Overview: Human AMACR full-length ORF ( AAH09471, 1 a.a. - 198 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 47.52 kDa
• AA Sequence: MALQGISVMELSGLAPGPFCAMVLA DFGARVVRVDRPGSRYDVSRLGRGK RSLVLDLKQPRGAAVLRRLCKRSDV LLEPFRRGVMEKLQLGPEILQRENP RLIYARLSGFGQSGSFCRLAGHDIN YLALSGGRNSMFKFFSVENSEIESV GSTSRTEHVGWWSTFLYDLQDSRWG IHGCWSNRTPVLRAADQRTWTKV
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AMACR alpha-methylacyl-CoA racemase [ Homo sapiens ]
• Official Symbol: AMACR
• Synonyms: AMACR; alpha-methylacyl-CoA racemase; RACE; 2-methylacyl-CoA racemase; RM; CBAS4; AMACRD
• Gene ID: 23600
• mRNA Refseq: NM_001167595
• Protein Refseq: NP_001161067
• MIM: 604489
• UniProt ID: Q9UHK6