Recombinant Human ANKS1B Protein, GST-tagged

• Cat.No.: ANKS1B-2649H
• Product Overview: Human EB-1 full-length ORF ( AAH26313, 1 a.a. - 510 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 81.84 kDa
• AA Sequence: MMWQCHPSAQDYRYYPVDGYSLLKR FPLHPLTGPRCPVQTVGQWLESIGL PQYENHLMANGFDNVQFMGSNVMED QDLLEIGILNSGHRQRILQAIQLLP KMRPIGHDGYHPTSVAEWLDSIELG DYTKAFLINGYTSMDLLKKIWEVEL INVLKINLIGHRKRILASLGDRLHD DPPQKPPRSITLREPSGNHTPPQLS PSLSQSTYTTGGSLDVPHIIMQGDA RRRRNENYFDDIPRSKLERQMAQSS VCEIWTNQNAGFPFSAIHQVHNTGD WGEPSITLRPPNEATASTPVQYWQH HPEKLIFQSCDYKAFYLGSMLIKEL RGTESTQDACAKMRANCQKSTEQMK KVPTIILSVSYKGVKFIDATNKNII AEHEIRNISCAAQDPEDLSTFAYIT KDLKSNHHYCHVFTAFDVNLAYEII LTLGQAFEVAYQLALQARKGGHSST LPESFENKPSKPIPKPRVSIRKSVQ IDPSEQKTLANLPWIVEPGQEAKRG INTKYETTIF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B [ Homo sapiens ]
• Official Symbol: ANKS1B
• Synonyms: ANKS1B; ankyrin repeat and sterile alpha motif domain containing 1B; ankyrin repeat and sterile alpha motif domain-containing protein 1B; AIDA 1; ANKS2; cajalin 2; EB 1; E2a-Pbx1-associated protein; amyloid-beta precursor protein intracellular domain associated protein 1; EB1; AIDA; EB-1; AIDA-1; cajalin-2; MGC26087
• Gene ID: 56899
• mRNA Refseq: NM_001204065
• Protein Refseq: NP_001190994
• MIM: 607815
• UniProt ID: Q7Z6G8