Recombinant Human ANKS1B Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ANKS1B Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ANKS1B-6455H
Product Overview : ANKS1B MS Standard C13 and N15-labeled recombinant protein (NP_064525) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 46.9 kDa
AA Sequence : MMWQCHLSAQ DYRYYPVDGY SLLKRFPLHP LTGPRCPVQT VGQWLESIGL PQYENHLMAN GFDNVQFMGS NVMEDQDLLE IGILNSGHRQ RILQAIQLLP KMRPIGHDGY HPTSVAEWLD SIELGDYTKA FLINGYTSMD LLKKIWEVEL INVLKINLIG HRKRILASLG DRLHDDPPQK PPRSITLRTG DWGEPSITLR PPNEATASTP VQYWQHHPEK LIFQSCDYKA FYLGSMLIKE LRGTESTQDA CAKMRANCQK STEQMKKVPT IILSVSYKGV KFIDATNKNI IAEHEIRNIS CAAQDPEDLS TFAYITKDLK SNHHYCHVFT AFDVNLAYEI ILTLGQAFEV AYQLALQARK GGHSSTLPES FENKPSKPIP KPRVSIRKSV DLLHASHTGQ EPSERHTEEA LRKFTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B [ Homo sapiens (human) ]
Official Symbol : ANKS1B
Synonyms : ANKS1B; ankyrin repeat and sterile alpha motif domain containing 1B; ankyrin repeat and sterile alpha motif domain-containing protein 1B; AIDA 1; ANKS2; cajalin 2; EB 1; E2a-Pbx1-associated protein; amyloid-beta precursor protein intracellular domain associated protein 1; EB1; AIDA; EB-1; AIDA-1; cajalin-2; MGC26087;
Gene ID : 56899
mRNA Refseq : NM_020140
Protein Refseq : NP_064525
MIM : 607815
UniProt ID : Q7Z6G8

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