Cat.No. : |
ANKS1B-6455H |
Product Overview : |
ANKS1B MS Standard C13 and N15-labeled recombinant protein (NP_064525) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : |
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
46.9 kDa |
AA Sequence : |
MMWQCHLSAQ DYRYYPVDGY SLLKRFPLHP LTGPRCPVQT VGQWLESIGL PQYENHLMAN GFDNVQFMGS NVMEDQDLLE IGILNSGHRQ RILQAIQLLP KMRPIGHDGY HPTSVAEWLD SIELGDYTKA FLINGYTSMD LLKKIWEVEL INVLKINLIG HRKRILASLG DRLHDDPPQK PPRSITLRTG DWGEPSITLR PPNEATASTP VQYWQHHPEK LIFQSCDYKA FYLGSMLIKE LRGTESTQDA CAKMRANCQK STEQMKKVPT IILSVSYKGV KFIDATNKNI IAEHEIRNIS CAAQDPEDLS TFAYITKDLK SNHHYCHVFT AFDVNLAYEI ILTLGQAFEV AYQLALQARK GGHSSTLPES FENKPSKPIP KPRVSIRKSV DLLHASHTGQ EPSERHTEEA LRKFTRTRPL EQKLISEEDL AANDILDYKD DDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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