Recombinant Human Annexin A10, His-tagged

• Cat.No.: ANXA10-5539H
• Product Overview: Recombinant humanANXA10 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.

Specification

• Cat. No.: ANXA10-5539H
• Description: ANXA10,also known as Annexin A10, belongs to the annexin family of calcium-bindingproteins contains several family members that are characterized by aconserved core domain, which binds phospholipids in a Ca2+-dependent manner,and a unique amino-terminal region, which may confer binding specificity.
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl.
• Molecular Weight: 39.8kDa(348aa) confirmed by MALDI-TOF
• Purity: > 95%by SDS-PAGE
• Concentration: 1 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMFCGDY VQGTIFPAPN FNPIMDAQML GGALQGFDCD KDMLINILTQ RCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFKDVMAGL MYPPPLYDAH ELWHAMKGVG TDENCLIEIL ASRTNGEIFQ MREAYCLQYS NNLQEDIYSETSGHFRDTLMNLVQGTREEGYTDPAMAAQD AMVLWEACQQ KTGEHKTMLQ MILCNKSYQQ LRLVFQEFQN ISGQDMVDAI NECYDGYFQELLVAIVLCVRDKPAYFAYRLYSAIHDFGFH NKTVIRILIA RSEIDLLTIR KRYKERYGKS LFHDIRNFAS GHYKKALLAI CAGDAEDY
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ANXA10 annexin A10 [ Homosapiens ]
• Official Symbol: ANXA10
• Synonyms: ANXA10; annexin A10; ANX14; annexin A10;annexin 14; annexin-10; annexin-14
• Gene ID: 11199
• mRNA Refseq: NM_007193
• Protein Refseq: NP_009124
• MIM: 608008
• UniProt ID: Q9UJ72
• Chromosome Location: 4q32.3
• Function: calcium ion binding; calcium-dependentphospholipid binding

Reviews

07/23/2021

The outstanding level of customer service adds extra reassurance and confidence in using the ANXA10 protein for my scientific investigations.

05/25/2021

The ANXA10 protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

07/26/2017

With the ANXA10 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

05/11/2016

the manufacturer of ANXA10 provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

Q&As

Is ANXA10 protein localized in a specific subcellular compartment?

ANXA10 protein is primarily known to localize to the cytoplasmic compartment of cells. It can also associate with cell membranes in some instances. However, the subcellular localization of ANXA10 may be cell type-specific and can vary depending on different physiological conditions.

Is ANXA10 protein involved in calcium signaling?

Annexin proteins, including ANXA10, have been shown to interact with calcium ions and are involved in calcium signaling pathways. They can regulate calcium fluxes across membranes and participate in calcium-mediated processes such as neurotransmitter release, muscle contraction, and cell migration. While there is limited information specifically regarding ANXA10's role in calcium signaling, it is possible that it may contribute to these processes.

Is ANXA10 protein expressed in all tissues?

The expression of ANXA10 protein has been reported to vary across different tissues. It appears to be more abundant in certain tissues, such as the liver and pancreas, while its expression in other tissues may be lower or undetectable.