| Description : |
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
75.1 kDa |
| AA Sequence : |
MAKPAQGAKYRGSIHDFPGFDPNQD AEALYTAMKGFGSDKEAILDIITSR SNRQRQEVCQSYKSLYGKDLIADLK YELTGKFERLIVGLMRPPAYCDAKE IKDAISGIGTDEKCLIEILASRTNE QMHQLVAAYKDAYERDLEADIIGDT SGHFQKMLVVLLQGTREEDDVVSED LVQQDVQDLYEAGELKWGTDEAQFI YILGNRSKQHLRLVFDEYLKTTGKP IEASIRGELSGDFEKLMLAVVKCIR STPEYFAERLFKAMKGLGTRDNTLI RIMVSRSELDMLDIREIFRTKYEKS LYSMIKNDTSGEYKKTLLKLSGGDD DAAGQFFPEAAQVAYQMWELSAVAR VELKGTVRPANDFNPDADAKALRKA MKGLGTDEDTIIDIITHRSNVQRQQ IRQTFKSHFGRDLMTDLKSEISGDL ARLILGLMMPPAHYDAKQLKKAMEG AGTDEKALIEILATRTNAEIRAINE AYKEDYHKSLEDALSSDTSGHFRRI LISLATGHREEGGENLDQAREDAQE IADTPSGDKTSLETRFMTILCTRSY PHLRRVFQEFIKMTNYDVEHTIKKE MSGDVRDAFVAIVQSVKNKPLFFAD KLYKSMKGAGTDEKTLTRIMVSRSE IDLLNIRREFIEKYDKSLHQAIEGD TSGDFLKALLALCGGEDTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
