Recombinant Human AP2M1, T7 -tagged
Cat.No. : | AP2M1-27356TH |
Product Overview : | Recombinant full length protein: Human AP2M1 proetein fused to T7 tag at N-terminus. |
- Specification
- Gene Information
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Description : | This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. |
Conjugation : | T7 |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the adaptor complexes medium subunit family.Contains 1 MHD (mu homology) domain. |
Gene Name : | AP2M1 adaptor-related protein complex 2, mu 1 subunit [ Homo sapiens ] |
Official Symbol : | AP2M1 |
Synonyms : | AP2M1; adaptor-related protein complex 2, mu 1 subunit; CLAPM1; AP-2 complex subunit mu; AP 2 mu 2 chain; AP50; clathrin adaptor complex AP2; mu subunit; clathrin assembly protein complex 2 medium chain; clathrin coat adaptor protein AP50; clathrin associ |
Gene ID : | 1173 |
mRNA Refseq : | NM_001025205 |
Protein Refseq : | NP_001020376 |
MIM : | 601024 |
Uniprot ID : | Q96CW1 |
Chromosome Location : | 3q28 |
Pathway : | Arf1 pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; EGFR downregulation, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; |
Function : | lipid binding; protein binding; transporter activity; |
Products Types
◆ Recombinant Protein | ||
AP2M1-1328H | Recombinant Human AP2M1 Protein (1-435 aa), His-tagged | +Inquiry |
AP2M1-357R | Recombinant Rat AP2M1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AP2M1-176R | Recombinant Rhesus Macaque AP2M1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AP2M1-351H | Recombinant Human AP2M1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AP2M1-393H | Recombinant Human AP2M1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
AP2M1-8814HCL | Recombinant Human AP2M1 293 Cell Lysate | +Inquiry |
AP2M1-8813HCL | Recombinant Human AP2M1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (20)
Ask a questionAP2M1 can be used in scientific research to study the regulation mechanism of intracellular protein and the pathogenesis of disease.
AP2M1 can interfere with tumor cell signaling pathways, thereby inhibiting tumor growth and spread.
AP2M1 research still needs to address safety, preparation methods and dosage challenges.
The personalized medicine is the development trend in the future, and we can expect the application prospect of AP2M1 in this field.
The side effects of recombinant AP2M1 are not known and further studies are needed to evaluate its safety.
It is theoretically possible to apply recombinant AP2M1 with gene therapy, but more research is needed to confirm this.
Mouse models are currently available to further understand the pharmacological properties of AP2M1 .
There are no results of studies on oral administration, but attempts to develop the pathway could be made.
AP2M1 can play a therapeutic role by interfering with intracellular signaling pathways, sometimes avoiding adverse drug reactions.
The current dosage and mode of use are still under investigation, and further clinical trials are needed to determine the best use.
Future studies could focus on optimizing the preparation method, study dose and safety, and further evaluate the clinical prospects of AP2M1 .
AP2M1 can bind to specific receptors in human cells to regulate signaling pathways.
AP2M1 may be used as part of the drug delivery system to achieve targeted drug delivery by regulating intracellular delivery mechanisms.
Yes, the recombinant AP2M1 protein can interact with other proteins to affect cell function.
AP2M1 research is still in its infancy, but there have been some promising discoveries.
AP2M1 is generally expressed and purified in cells by genetic engineering technology.
The stability of AP2M1 may be affected by a variety of factors and needs to be optimized through further research.
AP2M1 may have antiviral activity, but further validation and research is needed.
It is not currently in clinical use, but one can expect its potential in treating diseases such as cancer.
AP2M1 has high specificity and selectivity, and can be targeted for treatment.
Customer Reviews (4)
Write a reviewThe reproducibility of AP2M1 is very good, and the results remain consistent even after repeated experiments, which makes me more confident in the experimental results.
The short half-life and high clearance characteristics of AP2M1 enable it to reach the therapeutic concentration quickly and maintain a stable blood concentration, thus improving the therapeutic effect.
In the case of adding different chemicals or drugs, the stability of this protein is still very good, indicating that it has excellent anti-interference ability and stability.
AP2M1 in Western blot is very good, even if it is stored for a long time, it will not affect its performance.
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