Human AP2M1 Knockdown Cell Lysate

• Cat.No.: AP2M1-040HKCL
• Product Overview: WB-validated AP2M1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 50 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg AP2M1 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Huntington's disease
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: AP2M1 adaptor-related protein complex 2, mu 1 subunit [ Homo sapiens (human) ]
• Official Symbol: AP2M1
• Synonyms: AP2M1; adaptor-related protein complex 2, mu 1 subunit; CLAPM1; AP-2 complex subunit mu; AP 2 mu 2 chain; AP50; clathrin adaptor complex AP2; mu subunit; clathrin assembly protein complex 2 medium chain; clathrin coat adaptor protein AP50; clathrin associated/assembly/adaptor protein; medium 1; HA2 50 kDA subunit; mu2; plasma membrane adaptor AP 2 50kDA protein; adaptin-mu2; AP-2 mu chain; AP-2 mu 2 chain; clathrin coat assembly protein AP50; clathrin coat-associated protein AP50; adaptor protein complex AP-2 subunit mu; clathrin adaptor complex AP2, mu subunit; plasma membrane adaptor AP-2 50kDA protein; plasma membrane adaptor AP-2 50 kDa protein; adapter-related protein complex 2 mu subunit; clathrin-associated/assembly/adaptor protein, medium 1
• Gene ID: 1173
• mRNA Refseq: NM_001025205
• Protein Refseq: NP_001020376
• MIM: 601024
• UniProt ID: Q96CW1