Recombinant Human APAF1 protein, GST-tagged
Cat.No. : | APAF1-665H |
Product Overview : | Human APAF1 partial ORF ( NP_037361, 1138 a.a. - 1237 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.85 kDa |
AA Sequence : | GEIRIWNVSNGELLHLCAPLSEEGA ATHGGWVTDLCFSPDGKMLISAGGY IKWWNVVTGESSQTFYTNGTNLKKI HVSPDFKTYVTVDNLGILYILQTLE |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | APAF1 apoptotic peptidase activating factor 1 [ Homo sapiens ] |
Official Symbol : | APAF1 |
Synonyms : | APAF1; apoptotic peptidase activating factor 1; apoptotic peptidase activating factor , apoptotic protease activating factor; apoptotic protease-activating factor 1; APAF 1; CED4; APAF-1; DKFZp781B1145; |
Gene ID : | 317 |
mRNA Refseq : | NM_001160 |
Protein Refseq : | NP_001151 |
MIM : | 602233 |
UniProt ID : | O14727 |
Products Types
◆ Recombinant Protein | ||
APAF1-612M | Recombinant Mouse APAF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Apaf1-197R | Recombinant Rat Apaf1 Protein, His-tagged | +Inquiry |
APAF1-1329H | Recombinant Human APAF1 Protein (104-415 aa), His-tagged | +Inquiry |
APAF1-0784H | Recombinant Human APAF1 Protein (M1-S97), His tagged | +Inquiry |
APAF1-0783H | Recombinant Human APAF1 Protein (M1-S97), Tag Free | +Inquiry |
◆ Lysates | ||
APAF1-89HCL | Recombinant Human APAF1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket