Recombinant Human APBA2, GST-tagged

• Cat.No.: APBA2-9728H
• Product Overview: Recombinant Human APBA2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-66a.a.
• Description: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimers disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimers disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 [ Homo sapiens ]
• Official Symbol: APBA2
• Synonyms: APBA2; amyloid beta (A4) precursor protein-binding, family A, member 2; amyloid beta (A4) precursor protein binding, family A, member 2 (X11 like) , MINT2, X11 like , X11L; amyloid beta A4 precursor protein-binding family A member 2; D15S1518E; HsT16821; LIN 10; MGC:14091; mint-2; X11-like protein; adapter protein X11beta; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); X11L; MINT2; LIN-10; X11-BETA; MGC99508
• Gene ID: 321
• mRNA Refseq: NM_001130414
• Protein Refseq: NP_001123886
• MIM: 602712
• UniProt ID: Q99767
• Chromosome Location: 15q11-q12
• Function: protein binding