Recombinant Human APBB3 protein, GST-tagged
Cat.No. : | APBB3-671H |
Product Overview : | Human APBB3 full-length ORF ( AAH13158, 1 a.a. - 486 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 79.20 kDa |
AA Sequence : | MLGKDYMLAIILVNCDDDLWGDHSL EVEAGLPPGWRKIHDAAGTYYWHVP SGSTQWQRPTWELGDAEDPGTGTEG IWGLRPPKGRSFSSLESSLDRSNSL SWYGGESYIQSMEPGAKCFAVRSLG WVEVPEEDLAPGKSSIAVNNCIQQL AQTRSRSQPPDGAWGEGQNMLMILK KDAMSLVNPLDHSLIHCQPLVHIRV WGVGSSKGRDRDFAFVASDKDSCML KCHVFRCDVPAKAIASALHGLCAQI LSERVEVSGDASCCSPDPISPEDLP RQVELLDAVSQAAQKYEALYMGTLP VTKAMGMDVLNEAIGTLTARGDRNA WVPTMLSVSDSLMTAHPIQAEASTE EEPLWQCPVRLVTFIGVGRDPHTFG LIADLGRQSFQCAAFWCQPHAGGLS EAVQAACMVQYQKCLVASAARGKAW GAQARARLRLKRTSSMDSPGGPLPL PLLKGGVGGAGATPRKRGVFSLLDA FRLKPSLLHMP |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 [ Homo sapiens ] |
Official Symbol : | APBB3 |
Synonyms : | APBB3; amyloid beta (A4) precursor protein-binding, family B, member 3; amyloid beta A4 precursor protein-binding family B member 3; FE65L2; FE65-like protein 2; protein Fe65-like 2; amyloid precursor interacting protein; SRA; MGC87674; MGC150555; |
Gene ID : | 10307 |
mRNA Refseq : | NM_006051 |
Protein Refseq : | NP_006042 |
MIM : | 602711 |
UniProt ID : | O95704 |
Products Types
◆ Recombinant Protein | ||
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APBB3-711R | Recombinant Rat APBB3 Protein | +Inquiry |
APBB3-351R | Recombinant Rhesus monkey APBB3 Protein, His-tagged | +Inquiry |
APBB3-3439H | Recombinant Human APBB3, His-tagged | +Inquiry |
◆ Lysates | ||
APBB3-8800HCL | Recombinant Human APBB3 293 Cell Lysate | +Inquiry |
APBB3-8801HCL | Recombinant Human APBB3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (20)
Ask a questionRecombinant Apbb3 protein supports neuronal maturation and function by regulating axon morphology, intercellular communication, and signal transduction.
The effects of Apbb3 injection on the nervous system include neuronal activity and the regulation of the external environment.
Some studies have shown that low expression of the recombinant Apbb3 protein is associated with the onset of neurodegenerative diseases.
Recombinant Apbb3 protein is one of the important therapeutic targets for neurodegenerative diseases, and related drug development is ongoing.
Recombinant Apbb3 protein can be used as an auxiliary test for clinical diagnosis of neurology and prediction of neurodegenerative diseases.
Several studies have shown that the Apbb3 can help restore cerebral ischemia-reperfusion injury in rats by promoting nervous system regeneration and protective effects.
Apbb3 can play a role in regulating glial interaction, participating in neuronal development and protecting physiological processes in neural processes.
Some studies have shown that the expression of Apbb3 is associated with the occurrence and progression of nervous system tumors.
Apbb3 is composed of multiple domains, different domains have different functions, including ligand binding, signal transduction and so on.
The Apbb3 regulates the activity of a variety of signaling pathways in the synapses of neurons.
The Apbb3 plays an important role in both synapses and cellular bodies of neurons to regulate the development and function of neurons.
Several studies have shown that the Apbb3 can play an important role in the plasticity of neuronal synapses.
Recombinant protein Apbb3 plays a role in the development of the nervous system by regulating signaling pathways between nerve cells and non-nerve cells.
The recombinant Apbb3 protein can interact with a variety of proteins, including neuronal transport proteins and neurotransmitter receptors.
In addition to neurodegenerative diseases, Apbb3 is also associated with other neurological diseases, such as brain trauma and stroke.
The recombinant Apbb3 protein plays an important role in neurodegenerative diseases such as Alzheimer's disease.
Several studies have shown that the recombinant Apbb3 protein can play an important role in the mouse model of rabbit spinal cord injury induced by BCG vaccine, including promoting the proliferation of neural stem cells.
Recombinant Apbb3 proteins are involved in a variety of biological processes, including neurodevelopment, signaling pathway regulation, and the development of neurodegenerative diseases.
Recombinant Apbb3 proteins are regulated by multiple signaling pathways, including transcription factors, phosphorylation, and natural products.
The recombinant Apbb3 protein is highly specific and sensitive, and can accurately identify the relevant protein in the serum of patients with neurodegenerative diseases.
Customer Reviews (4)
Write a reviewThe green production process of APBB2 realizes the minimization of waste and minimal impact on the environment, which truly achieves green production.
Reproducibility of APBB2 is very good, and the results are highly consistent regardless of the conditions under which it is tested or applied, demonstrating its excellent stability and reliability.
Short half-life and high clearance characteristics of APBB2 make it have greater potential in the treatment of tumors, infections and other diseases, and is expected to become a new generation of therapeutic drugs.
Catalytic activity of APBB2 is very excellent, which can greatly improve the rate and selectivity of chemical reactions, and its scientific research value is incomparable.
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