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Recombinant Human APBB3 protein, GST-tagged

Cat.No. : APBB3-671H
Product Overview : Human APBB3 full-length ORF ( AAH13158, 1 a.a. - 486 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 79.20 kDa
AA Sequence : MLGKDYMLAIILVNCDDDLWGDHSL EVEAGLPPGWRKIHDAAGTYYWHVP SGSTQWQRPTWELGDAEDPGTGTEG IWGLRPPKGRSFSSLESSLDRSNSL SWYGGESYIQSMEPGAKCFAVRSLG WVEVPEEDLAPGKSSIAVNNCIQQL AQTRSRSQPPDGAWGEGQNMLMILK KDAMSLVNPLDHSLIHCQPLVHIRV WGVGSSKGRDRDFAFVASDKDSCML KCHVFRCDVPAKAIASALHGLCAQI LSERVEVSGDASCCSPDPISPEDLP RQVELLDAVSQAAQKYEALYMGTLP VTKAMGMDVLNEAIGTLTARGDRNA WVPTMLSVSDSLMTAHPIQAEASTE EEPLWQCPVRLVTFIGVGRDPHTFG LIADLGRQSFQCAAFWCQPHAGGLS EAVQAACMVQYQKCLVASAARGKAW GAQARARLRLKRTSSMDSPGGPLPL PLLKGGVGGAGATPRKRGVFSLLDA FRLKPSLLHMP
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 [ Homo sapiens ]
Official Symbol : APBB3
Synonyms : APBB3; amyloid beta (A4) precursor protein-binding, family B, member 3; amyloid beta A4 precursor protein-binding family B member 3; FE65L2; FE65-like protein 2; protein Fe65-like 2; amyloid precursor interacting protein; SRA; MGC87674; MGC150555;
Gene ID : 10307
mRNA Refseq : NM_006051
Protein Refseq : NP_006042
MIM : 602711
UniProt ID : O95704

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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What is the mechanism of the effect of Apbb3 on neuronal maturation and support? 12/05/2022

Recombinant Apbb3 protein supports neuronal maturation and function by regulating axon morphology, intercellular communication, and signal transduction.

What is the effect of the injection of Apbb3 into neurons on the nervous system? 08/03/2022

The effects of Apbb3 injection on the nervous system include neuronal activity and the regulation of the external environment.

What is the relationship between the expression level of Apbb3 and the pathogenesis of neurodegenerative diseases? 07/14/2022

Some studies have shown that low expression of the recombinant Apbb3 protein is associated with the onset of neurodegenerative diseases.

Can recombinant Apbb3 be a therapeutic target for neurodegenerative diseases? 07/09/2022

Recombinant Apbb3 protein is one of the important therapeutic targets for neurodegenerative diseases, and related drug development is ongoing.

What is the role of Apbb3 in clinical diagnosis of neurology? 07/09/2022

Recombinant Apbb3 protein can be used as an auxiliary test for clinical diagnosis of neurology and prediction of neurodegenerative diseases.

What is the role of Apbb3 in cerebral ischemia-reperfusion injury in rats? 07/03/2022

Several studies have shown that the Apbb3 can help restore cerebral ischemia-reperfusion injury in rats by promoting nervous system regeneration and protective effects.

What role does recombinant Apbb3 play in neural processes? 06/07/2022

Apbb3 can play a role in regulating glial interaction, participating in neuronal development and protecting physiological processes in neural processes.

What is the relationship between the expression of Apbb3 and nervous system tumors? 05/24/2022

Some studies have shown that the expression of Apbb3 is associated with the occurrence and progression of nervous system tumors.

What is the relationship between structure and function of Apbb3 ? 05/21/2022

Apbb3 is composed of multiple domains, different domains have different functions, including ligand binding, signal transduction and so on.

What is the interaction between Apbb3 and synapses? 08/23/2021

The Apbb3 regulates the activity of a variety of signaling pathways in the synapses of neurons.

What is the relationship between the localization and function of Apbb3 in neurons? 08/21/2021

The Apbb3 plays an important role in both synapses and cellular bodies of neurons to regulate the development and function of neurons.

Does Apbb3 play a role in synaptic plasticity of neurons? 08/05/2021

Several studies have shown that the Apbb3 can play an important role in the plasticity of neuronal synapses.

What is the mechanism of action of Apbb3 in nervous system development? 07/15/2021

Recombinant protein Apbb3 plays a role in the development of the nervous system by regulating signaling pathways between nerve cells and non-nerve cells.

What is the mechanism of interaction between Apbb3 and other proteins? 04/05/2021

The recombinant Apbb3 protein can interact with a variety of proteins, including neuronal transport proteins and neurotransmitter receptors.

What is the association between Apbb3 and other neurological diseases? 01/10/2021

In addition to neurodegenerative diseases, Apbb3 is also associated with other neurological diseases, such as brain trauma and stroke.

What role does recombinant Apbb3 play in human diseases? 09/12/2020

The recombinant Apbb3 protein plays an important role in neurodegenerative diseases such as Alzheimer's disease.

What is the role of Apbb3 in a mouse model of rabbit spinal cord injury induced by BCG vaccine? 09/01/2020

Several studies have shown that the recombinant Apbb3 protein can play an important role in the mouse model of rabbit spinal cord injury induced by BCG vaccine, including promoting the proliferation of neural stem cells.

What biological processes does Apbb3 participate in? 09/04/2019

Recombinant Apbb3 proteins are involved in a variety of biological processes, including neurodevelopment, signaling pathway regulation, and the development of neurodegenerative diseases.

How is the Apbb3 regulated? 06/23/2019

Recombinant Apbb3 proteins are regulated by multiple signaling pathways, including transcription factors, phosphorylation, and natural products.

What are the specificity and sensitivity of Apbb3 ? 02/21/2019

The recombinant Apbb3 protein is highly specific and sensitive, and can accurately identify the relevant protein in the serum of patients with neurodegenerative diseases.

Customer Reviews (4)

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Reviews
12/18/2022

    The green production process of APBB2 realizes the minimization of waste and minimal impact on the environment, which truly achieves green production.

    09/12/2021

      Reproducibility of APBB2 is very good, and the results are highly consistent regardless of the conditions under which it is tested or applied, demonstrating its excellent stability and reliability.

      11/09/2019

        Short half-life and high clearance characteristics of APBB2 make it have greater potential in the treatment of tumors, infections and other diseases, and is expected to become a new generation of therapeutic drugs.

        05/27/2019

          Catalytic activity of APBB2 is very excellent, which can greatly improve the rate and selectivity of chemical reactions, and its scientific research value is incomparable.

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