Recombinant Human APOA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: APOA1-4356H
• Product Overview: APOA1 MS Standard C13 and N15-labeled recombinant protein (NP_000030) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 30.8 kDa
• AA Sequence: MKAAVLTLAVLFLTGSQARHFWQQD EPPQSPWDRVKDLATVYVDVLKDSG RDYVSQFEGSALGKQLNLKLLDNWD SVTSTFSKLREQLGPVTQEFWDNLE KETEGLRQEMSKDLEEVKAKVQPYL DDFQKKWQEEMELYRQKVEPLRAEL QEGARQKLHELQEKLSPLGEEMRDR ARAHVDALRTHLAPYSDELRQRLAA RLEALKENGGARLAEYHAKATEHLS TLSEKAKPALEDLRQGLLPVLESFK VSFLSALEEYTKKLNTQTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: APOA1 apolipoprotein A-I [ Homo sapiens (human) ]
• Official Symbol: APOA1
• Synonyms: APOA1; apolipoprotein A-I; apo-AI; apoA-I; MGC117399
• Gene ID: 335
• mRNA Refseq: NM_000039
• Protein Refseq: NP_000030
• MIM: 107680
• UniProt ID: P02647