Recombinant Human APOBEC3B protein, DYKDDDDK-tagged

• Cat.No.: APOBEC3B-01H
• Product Overview: Recombinant protein from the full-length sequence of homo sapiens apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3B (APOBEC3B), transcript variant 1 (NM_004900), with a DYKDDDDK tag, was expressed in HEK293.

Specification

• Description: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Human cells
• Species: Human
• Tag: DYKDDDDK
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives.
• Molecular Mass: 45.7 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Gene Information

• Gene Name: APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B [ Homo sapiens (human) ]
• Official Symbol: APOBEC3B
• Synonyms: A3B; APOBEC1L; ARCD3; ARP4; bK150C2.2; DJ742C19.2; PHRBNL
• Gene ID: 9582
• mRNA Refseq: NM_004900
• Protein Refseq: NP_004891
• MIM: 607110
• UniProt ID: Q9UH17