Recombinant Human APOBEC3B protein, GST-tagged

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Recombinant Human APOBEC3B protein, GST-tagged

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Cat.No. : APOBEC3B-697H
Product Overview : Human APOBEC3B full-length ORF ( AAH53859.1, 1 a.a. - 251 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 56.2 kDa
AA Sequence : MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW DTGVFRGQVY FEPQYHAEMC FLSWFCGNQL PAYKCFQITW FVSWTPCPDC VAKLAEFLSE HPNVTLTISA ARLYYYWERD YRRALCRLSQ AGARVKIMDY EEFAYCWENF VYNEGQQFMP WYKFDENYAF LHRTLKEILR LRIFSVAFTA AMRSCASWTW FLLCSWTRPR STGSLGSSPG APASPGAVPG KCVRSFRRTH T
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B [ Homo sapiens ]
Official Symbol : APOBEC3B
Synonyms : APOBEC3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; probable DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 3; PHRBNL; probable DNA dC-> dU-editing enzyme APOBEC-3B; phorbolin 2; phorbolin-2/3; cytidine deaminase; phorbolin-1-related protein; ARP4; ARCD3; APOBEC1L; bK150C2.2; DJ742C19.2;
Gene ID : 9582
mRNA Refseq : NM_004900
Protein Refseq : NP_004891
MIM : 607110
UniProt ID : Q9UH17
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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