Recombinant Human APS protein, GST-tagged

• Cat.No.: APS-730H
• Product Overview: Human APS partial ORF ( NP_066189, 311 a.a. - 410 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.74 kDa
• AA Sequence: EEDTELSCTRGGCLASRVASCSCEL LTDAVDLPRPPETTAVGAVVTAPHS RGRDAVRESLIHVPLETFLQTLESP GGSGSDSNNTGEQGAETDPEAEPEL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: SH2B2 SH2B adaptor protein 2 [ Homo sapiens ]
• Official Symbol: SH2B2
• Synonyms: SH2B2; SH2B adaptor protein 2; SH2B adapter protein 2; adaptor protein with pleckstrin homology and src; APS; SH2 and PH domain-containing adapter protein APS; adapter protein with pleckstrin homology and Src homology 2 domains; adaptor protein with pleckstrin homology and src homology 2 domains
• Gene ID: 10603
• mRNA Refseq: NM_020979
• Protein Refseq: NP_066189
• MIM: 605300
• UniProt ID: O14492