Recombinant Human SH2B2 Protein, MYC/DDK-tagged

• Cat.No.: SH2B2-1341H
• Product Overview: Recombinant human SH2B2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 72.1 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SH2B2 SH2B adaptor protein 2 [ Homo sapiens ]
• Official Symbol: SH2B2
• Synonyms: APS
• Gene ID: 10603
• mRNA Refseq: NM_020979
• Protein Refseq: NP_066189
• MIM: 605300
• UniProt ID: O14492