Description : |
This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
61 kDa |
AA Sequence : |
MSEPPVYCNLVDLRRCPRSPPPGPA CPLLQRLDAWEQHLDPNSGRCFYIN SLTGCKSWKPPRRSRSETNPGSMEG TQTLKRNNDVLQPQAKGFRSDTGTP EPLDPQGSLSLSQRTSQLDPPALQA PRPLPQLLDDPHEVEKSGLLNMTKI AQGGRKLRKNWGPSWVVLTGNSLVF YREPPPTAPSSGWGPAGSRPESSVD LRGAALAHGRHLSSRRNVLHIRTIP GHEFLLQSDHETELRAWHRALRTVI ERLDRENPLELRLSGSGPAELSAGE DEEEESELVSKPLLRLSSRRSSIRG PEGTEQNRVRNKLKRLIAKRPPLQS LQERGLLRDQVFGCQLESLCQREGD TVPSFLRLCIAAVDKRGLDVDGIYR VSGNLAVVQKLRFLVDRERAVTSDG RYVFPEQPGQEGRLDLDSTEWDDIH VVTGALKLFLRELPQPLVPPLLLPH FRAALALSESEQCLSQIQELIGSMP KPNHDTLRYLLEHLCRVIAHSDKNR MTPHNLGIVFGPTLFRPEQETSDPA AHALYPGQLVQLMLTNFTSLFPTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |