Recombinant Human ARHGDIA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARHGDIA-2016H
• Product Overview: ARHGDIA MS Standard C13 and N15-labeled recombinant protein (NP_004300) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23.2 kDa
• AA Sequence: MAEQEPTAEQLAQIAAENEEDEHSV NYKPPAQKSIQEIQELDKDDESLRK YKEALLGRVAVSADPNVPNVVVTGL TLVCSSAPGPLELDLTGDLESFKKQ SFVLKEGVEYRIKISFRVNREIVSG MKYIQHTYRKGVKIDKTDYMVGSYG PRAEEYEFLTPVEEAPKGMLARGSY SIKSRFTDDDKTDHLSWEWNLTIKK DWKDTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARHGDIA Rho GDP dissociation inhibitor alpha [ Homo sapiens (human) ]
• Official Symbol: ARHGDIA
• Synonyms: ARHGDIA; Rho GDP dissociation inhibitor (GDI) alpha; GDIA1; rho GDP-dissociation inhibitor 1; RHOGDI; rho GDI 1; rho-GDI alpha; RHOGDI-1; MGC117248
• Gene ID: 396
• mRNA Refseq: NM_004309
• Protein Refseq: NP_004300
• MIM: 601925
• UniProt ID: P52565