Recombinant Human ARHGEF11 protein, GST-tagged ARHGEF11-780H

Recombinant Human ARHGEF11 protein, GST-tagged

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Recombinant Human ARHGEF11 protein, GST-tagged

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Cat.No. : ARHGEF11-780H
Product Overview : Human ARHGEF11 partial ORF ( AAH57394, 651 a.a. - 750 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.63 kDa
AA Sequence : RSESLKGREEMKRSR KAENVPRSRSDVDMD AAAEATRLHQSASSS TSSLSTRSLENPTPP FTPKMGRRSIESPSL GFCTDTLLPHLLEDD LGQLSDLEPE
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 [ Homo sapiens ]
Official Symbol : ARHGEF11
Synonyms : ARHGEF11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; GTRAP48; KIAA0380; PDZ RHOGEF; Rho guanine exchange factor (GEF) 11; RhoGEF glutamate transport modulator; RhoA-specific guanine nucleotide exchange factor; glutamate transporter EAAT4-associated protein 48; PDZ-RHOGEF; DKFZp667F1223;
Gene ID : 9826
mRNA Refseq : NM_014784
Protein Refseq : NP_055599
MIM : 605708
UniProt ID : O15085

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