Recombinant Human ARHGEF7 Protein, MYC/DDK-tagged

• Cat.No.: ARHGEF7-3892H
• Product Overview: Recombinant protein of human Rho guanine nucleotide exchange factor (GEF) 7 (ARHGEF7), transcript variant 2 with C-MYC/DDK tag was expressed in HEK293T.

Specification

• Description: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
• Source: HEK293T
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 87.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at –80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: ARHGEF7
• Official Symbol: ARHGEF7 Rho guanine nucleotide exchange factor 7 [ Homo sapiens (human) ]
• Synonyms: ARHGEF7; Rho guanine nucleotide exchange factor 7; P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314
• Gene ID: 8874
• mRNA Refseq: NM_145735
• Protein Refseq: NP_663788
• MIM: 605477
• UniProt ID: Q14155