Recombinant Human ARMC10 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARMC10-3988H
• Product Overview: ARMC10 MS Standard C13 and N15-labeled recombinant protein (NP_114111) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 37.4 kDa
• AA Sequence: MGGPRGAGWVAAGLLLGAGACYCIY RLTRGRRRGDRELGIRSSKSAGALE EGTSEGQLCGRSARPQTGGTWESQW SKTSQPEDLTDGSYDDVLNAEQLQK LLYLLESTEDPVIIERALITLGNNA AFSVNQAIIRELGGIPIVANKINHS NQSIKEKALNALNNLSVNVENQIKI KIYISQVCEDVFSGPLNSAVQLAGL TLLTNMTVTNDHQHMLHSYITDLFQ VLLTGNGNTKVQVLKLLLNLSENPA MTEGLLRAQVDSSFLSLYDSHVAKE ILLRVLTLFQNIKNCLKIEGHLAVQ PTFTEGSLFFLLHGEECAQKIRALV DHHDAEVKEKVVTIIPKITRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARMC10 armadillo repeat containing 10 [ Homo sapiens (human) ]
• Official Symbol: ARMC10
• Synonyms: ARMC10; armadillo repeat containing 10; armadillo repeat-containing protein 10; MGC3195; specific Splicing Variant involved in Hepatocarcinogenesis; SVH; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis; PNAS112; PNAS-112; PSEC0198; FLJ37850
• Gene ID: 83787
• mRNA Refseq: NM_031905
• Protein Refseq: NP_114111
• MIM: 611864
• UniProt ID: Q8N2F6