Recombinant Human ASB5 protein, GST-tagged
Cat.No. : | ASB5-894H |
Product Overview : | Human ASB5 full-length ORF (BAC04791.1, 1 a.a. - 329 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 62.7 kDa |
AA Sequence : | MSVLEENRPFAQQLSNVYFTILSLF CFKLFVKISLAILSHFYIVKGNRKE AARIAAEFYGVTQGQGSWADRSPLH EAASQGRLLALRTLLSQGYNVNAVT LDHVTPLHEACLGDHVACARTLLEA GANVNAITIDGVTPLFNACSQGSPS CAELLLEYGAKAQLESCLPSPTHEA ASKGHHECLDILISWGIDVDQEIPH LGTPLYVACMSQQFHCIWKLLYAGA DVQKGKYWDTPLHAAAQQSSTEIVN LLLEFGADINAKNTELLRPIDVATS SSMVERILLQHEATPSSLYQLCRLC IRSYIGKPRLHLIPQLQLPTLLKNF LQYR |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ASB5 ankyrin repeat and SOCS box containing 5 [ Homo sapiens ] |
Official Symbol : | ASB5 |
Synonyms : | ASB5; ankyrin repeat and SOCS box containing 5; ankyrin repeat and SOCS box protein 5; SOCS box protein ASB-5; ankyrin repeat and SOCS box-containing 5; ASB-5; |
Gene ID : | 140458 |
mRNA Refseq : | NM_080874 |
Protein Refseq : | NP_543150 |
UniProt ID : | Q8WWX0 |
Products Types
◆ Recombinant Protein | ||
ASB5-2529H | Recombinant Human ASB5 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (8)
Ask a questionASB5 can interact with different proteins, including ankyrin repeat and SOCS box-containing protein 10 (ASB10), which can modulate ASB5 activity in muscle development.
Yes, several genetic variations in the ASB5 gene have been identified. Some of these variations are associated with muscle-related disorders and cardiac abnormalities.
While ASB5's role in neurodevelopment or neurological disorders is not extensively studied, it may play a part in neuronal differentiation and function. Further research is required to determine its implications in neurological conditions.
Yes, studies have shown that ASB5 is important for muscle development and differentiation, particularly in the formation of skeletal muscle fibers.
Altered ASB5 expression or function has been observed in various conditions, including myopathies, neuropathies, and cardiac diseases. However, further research is needed to fully understand the extent of its involvement in these disorders.
While ASB5 is primarily known for its role in muscle development and protein degradation, it may also participate in other processes, such as cell proliferation and differentiation.
Yes, ASB5 has been implicated in cardiac diseases, including dilated cardiomyopathy and heart failure. It may contribute to the degradation of specific proteins involved in cardiac muscle contraction.
Yes, ASB5 expression can be regulated by signaling pathways involved in muscle development, such as the Notch signaling pathway.
Customer Reviews (3)
Write a reviewTheir expertise and commitment to customer satisfaction are truly commendable, ensuring that I have access to the necessary resources to overcome any experimental hurdles that may arise.
he ASB5 protein is an exceptional choice that meets the highest standards of quality, perfectly catering to my experimental requirements.
the ASB5 protein's well-documented properties and thoroughly tested functionality give me the confidence to integrate it seamlessly into my experimental setup.
Ask a Question for All ASB5 Products
Required fields are marked with *
My Review for All ASB5 Products
Required fields are marked with *
Inquiry Basket