Recombinant Human ASB7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ASB7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ASB7-3244H
Product Overview : ASB7 MS Standard C13 and N15-labeled recombinant protein (NP_078984) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 30.7 kDa
AA Sequence : MLHHHCRRNP ELQEELQIQA AVAAGDVHTV RKMLEQGYSP NGRDANGWTL LHFSAARGKE RCVRVFLEHG ADPTVKDLIG GFTALHYAAM HGRARIARLM LESEYRSDII NAKSNDGWTP LHVAAHYGRD SFVRLLLEFK AEVDPLSDKG TTPLQLAIIR ERSSCVKILL DHNANIDIQN GFLLRYAVIK SNHSYCRMFL QRGADTNLGR LEDGQTPLHL SALRDDVLCA RMLYNYGADT NTRNYEGQTP LAVSISISGS SRPCLDFLQE VTSMTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ASB7 ankyrin repeat and SOCS box containing 7 [ Homo sapiens (human) ]
Official Symbol : ASB7
Synonyms : ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; ASB-7; ankyrin repeat and SOCS box-containing 7; FLJ22551; FLJ25192;
Gene ID : 140460
mRNA Refseq : NM_024708
Protein Refseq : NP_078984
MIM : 615052
UniProt ID : Q9H672

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