Recombinant Human ASCC1, His-tagged
Cat.No. : | ASCC1-2303H |
Product Overview : | Recombinant human ASCC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | ASCC1 is a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in ASCC1 are associated with Barrett esophagus and esophageal adenocarcinoma. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 43.6 kDa |
Protein length : | 380aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMEVLRPQ LIRIDGRNYR KNPVQEQTYQ HEEDEEDFYQ GSMECADEPC DAYEVEQTPQ GFRSTLRAPS LLYKHIVGKR GDTRKKIEME TKTSISIPKP GQDGEIVITG QHRNGVISAR TRIDVLLDTF RRKQPFTHFL AFFLNEVEVQ EGFLRFQEEV LAKCSMDHGV DSSIFQNPKK LHLTIGMLVL LSEEEIQQTC EMLQQCKEEF INDISGGKPL EVEMAGIEYM NDDPGMVDVL YAKVHMKDGS NRLQELVDRV LERFQASGLI VKEWNSVKLH ATVMNTLFRK DPNAEGRYNL YTAEGKYIFK ERESFDGRNI LKLFENFYFG SLKLNSIHIS QRFTVDSFGN YASCGQIDFS |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml |
Gene Name : | ASCC1 activating signal cointegrator 1 complex subunit 1 [ Homo sapiens ] |
Official Symbol : | ASCC1 |
Synonyms : | ASCC1; activating signal cointegrator 1 complex subunit 1; ASC1p50; CGI 18; Em:AC022392.3; ASC-1 complex subunit P50; trip4 complex subunit p50; p50; CGI-18; |
Gene ID : | 51008 |
mRNA Refseq : | NM_001198798 |
Protein Refseq : | NP_001185727 |
MIM : | 614215 |
UniProt ID : | Q8N9N2 |
Chromosome Location : | 10pter-q25.3 |
Function : | RNA binding; |
Products Types
◆ Recombinant Protein | ||
Ascc1-1737M | Recombinant Mouse Ascc1 Protein, Myc/DDK-tagged | +Inquiry |
ASCC1-254R | Recombinant Rhesus Macaque ASCC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASCC1-782M | Recombinant Mouse ASCC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASCC1-9922H | Recombinant Human ASCC1, GST-tagged | +Inquiry |
ASCC1-2382Z | Recombinant Zebrafish ASCC1 | +Inquiry |
◆ Lysates | ||
ASCC1-8656HCL | Recombinant Human ASCC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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