Recombinant Human ASGR2 Protein, His-tagged

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Recombinant Human ASGR2 Protein, His-tagged

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Cat.No. : ASGR2-197H
Product Overview : Recombinant Human ASGR2(Met1~Ala311) fused with His tag at N-terminal was expressed in E. coli.
Description : This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 38.9kDa
Protein length : Met1~Ala311
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Figure :

Gene Name : ASGR2 asialoglycoprotein receptor 2 [ Homo sapiens ]
Official Symbol : ASGR2
Synonyms : ASGR2; asialoglycoprotein receptor 2; CLEC4H2; hepatic lectin H2; HBxAg-binding protein; C-type lectin domain family 4 member H2; HL-2; HBXBP; ASGPR2; ASGP-R2; FLJ60040;
Gene ID : 433
mRNA Refseq : NM_001181
Protein Refseq : NP_001172
MIM : 108361
UniProt ID : P07307

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