Recombinant Human ASH2L Protein, Full Length, N-His tagged

• Cat.No.: ASH2L-30HFL
• Product Overview: Recombinant Human ASH2L Protein, Full Length, with N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Full Length
• Description: Enables beta-catenin binding activity and transcription cis-regulatory region binding activity. Contributes to histone methyltransferase activity (H3-K4 specific). Involved in histone H3-K4 methylation; positive regulation of cell population proliferation; and response to estrogen. Acts upstream of or within cellular response to DNA damage stimulus. Located in nucleus. Part of MLL3/4 complex and Set1C/COMPASS complex.
• Form: Aqueous buffer solution
• Molecular Mass: 61 kDa
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Notes: Avoid freeze/thaw cycles
• Usage: Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.
• Shipping: At -80 centigrade
• References: 1. Ikegawa, S., et al., Cytogenet Cell Genet. 1999 ; 84(3-4) : 167-72.
  2. Chen, Y., et al., Cell Res. 2012 Mar ; 22(3) : 598-602.

Gene Information

• Gene Name: ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: ASH2L
• Synonyms: ASH2L; ash2 (absent, small, or homeotic)-like (Drosophila); ash2 (absent, small, or homeotic, Drosophila, homolog) like , ASH2L1; set1/Ash2 histone methyltransferase complex subunit ASH2; ASH2; ASH2L2; Bre2; ASH2-like protein; ASH2L1
• Gene ID: 9070
• mRNA Refseq: NM_001105214
• Protein Refseq: NP_001098684
• MIM: 604782
• UniProt ID: Q9UBL3