Recombinant Human ASIC4 Protein, Myc/DDK-tagged, C13 and N15-labeled ASIC4-4179H

Specification Gene Information Related Products

Cat.No. :	ASIC4-4179H
Product Overview :	ACCN4 MS Standard C13 and N15-labeled recombinant protein (NP_061144) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	72 kDa
AA Sequence :	MLSGAAGAAR RGGAALAPSL TRSLAGTHAG ADSCAGADKG SHKETIEERD KRQQRQQRQR QHQGCGAAGS GSDSPTSGPH PVPVLFPLAL SLEEQPLPPL PLGRAPGLLA REGQGREALA SPSSRGQMPI EIVCKIKFAE EDAKPKEKEA GDEQSLLGAV APGAAPRDLA TFASTSTLHG LGRACGPGPH GLRRTLWALA LLTSLAAFLY QAAGLARGYL TRPHLVAMDP AAPAPVAGFP AVTLCNINRF RHSALSDADI FHLANLTGLP PKDRDGHRAA GLRYPEPDMV DILNRTGHQL ADMLKSCNFS GHHCSASNFS VVYTRYGKCY TFNADPRSSL PSRAGGMGSG LEIMLDIQQE EYLPIWRETN ETSFEAGIRV QIHSQEEPPY IHQLGFGVSP GFQTFVSCQE QRLTYLPQPW GNCRAESELR EPELQGYSAY SVSACRLRCE KEAVLQRCHC RMVHMPDSLG GGPEGPCFCP TPCNLTRYGK EISMVRIPNR GSARYLARKY NRNETYIREN FLVLDVFFEA LTSEAMEQRA AYGLSALLGD LGGQMGLFIG ASILTLLEIL DYIYEVSWDR LKRVWRRPKT PLRTSTGGIS TLGLQELKEQ SPCPSLGRAE GGGVSSLLPN HHHPHGPPGG LFEDFACTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	ASIC4 acid sensing ion channel subunit family member 4 [ Homo sapiens (human) ]
Official Symbol :	ASIC4
Synonyms :	ASIC4; acid sensing ion channel subunit family member 4; ACCN4; BNAC4; acid-sensing ion channel 4; acid sensing ion channel family member 4; acid-sensing (proton-gated) ion channel family member 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; brain sodium channel 4
Gene ID :	55515
mRNA Refseq :	NM_018674
Protein Refseq :	NP_061144
MIM :	606715
UniProt ID :	Q96FT7