Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human ASPH Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : ASPH-4503H
Product Overview : ASPH MS Standard C13 and N15-labeled recombinant protein (NP_115857) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 33.6 kDa
AA Sequence : MAEDKETKHGGHKNGRKGGLSGTSF FTWFMVIALLGVWTSVAVVWFDLVD YEEVLAKAKDFRYNLSEVLQGKLGI YDADGDGDFDVDDAKVLLGLKERST SEPAVPPEEAEPHTEPEEQVPVEAE PQNIEDEAKEQIQSLLHEMVHAEHV EGEDLQQEDGPTGEPQQEDDEFLMA TDVDDRFETLEPEVSHEETEHSYHV EETVSQDCNQDMEEMMSEQENPDSS EPVVEDERLHHDTDDVTYQVYEEQA VYEPLENEGIEITEVTAPPEDNPVE DSQVIVEEVSIFPVEEQQEVPPDTT RTRPLEQKLISEEDLAANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : ASPH aspartate beta-hydroxylase [ Homo sapiens (human) ]
Official Symbol : ASPH
Synonyms : ASPH; aspartate beta-hydroxylase; aspartyl/asparaginyl beta-hydroxylase; BAH; CASQ2BP1; HAAH; humbug; JCTN; junctate; junctin; A beta H-J-J; cardiac junctin; ASP beta-hydroxylase; peptide-aspartate beta-dioxygenase; aspartyl/asparaginyl-beta-hydroxylase; AAH;
Gene ID : 444
mRNA Refseq : NM_032468
Protein Refseq : NP_115857
MIM : 600582
UniProt ID : Q12797

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All ASPH Products

Required fields are marked with *

My Review for All ASPH Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends