Recombinant Human ASPSCR1 protein, GST-tagged

• Cat.No.: ASPSCR1-920H
• Product Overview: Human ASPSCR1 full-length ORF ( AAH18722, 1 a.a. - 553 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 86.57 kDa
• AA Sequence: MAAPAGGGGSAVSVLAPNGRRHTVK VTPSTVLLQVLEDTCRRQDFNPCEY DLKFQRSVLDLSLQWRFANLPNNAK LEMVPASRSREGPENMVRIALQLDD GSRLQDSFCSGQTLWELLSHFPQIR ECLQHPGGATPVCVYTRDEVTGEAA LRGTTLQSLGLTGGSATIRFVMKCY DPVGKTPGSLGSSASAGQAAASAPL PLESGELSRGDLSRPEDADTSGPCC EHTQEKQSTRAPAAAPFVPFSGGGQ RQGGPPGPTRPLTSSSAKLPKSLSS PGGPSKPKKSKSGQDPQQEQEQERE RDPQQEQERERPVDREPVDREPVVC HPDLEERLQAWPAELPDEFFELTVD DVRRRLAQLKSERKRLEEAPLVTKA FREAQIKEKLERYPKVALRVLFPDR YVLQGFFRPSETVGDLRDFVRSHLG NPELSFYLFITPPKTVLDDHTQTLF QANLFPAALVHLGAEEPAGVYLEPG LLEHAISPSAADVLVARYMSRAAGS PSPLPAPDPAPKSEPAAEEGALVPP EPIPGTAQPVKRSLGKVPKWLKLPA SKR
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 [ Homo sapiens ]
• Official Symbol: ASPSCR1
• Synonyms: ASPSCR1; alveolar soft part sarcoma chromosome region, candidate 1; tether containing UBX domain for GLUT4; ASPL; ASPS; UBX domain protein 9; UBXD9; UBXN9; UBX domain-containing protein 9; alveolar soft part sarcoma locus; renal cell carcinoma, papillary, 17; renal papillary cell carcinoma protein 17; renal cell carcinoma gene on chromosome 17; alveolar soft part sarcoma chromosomal region candidate gene 1 protein; TUG; RCC17; ASPCR1; FLJ45380
• Gene ID: 79058
• mRNA Refseq: NM_001251888
• Protein Refseq: NP_001238817
• MIM: 606236
• UniProt ID: Q9BZE9