"ATF3" Related Products

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Recombinant Human ATF3 protein, His-SUMO-tagged

Cat.No.: ATF3-23H
Product Overview: Recombinant Human ATF3, fused with His-SUMO tag, was expressed in E. coli.
Description: This protein binds the cAMP response element (CRE) (consensus: 5"-GTGACGT[AC][AG]-3"), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Source: E.coli
Species: Human
Tag: His-SUMO
Form: 20mM Tris.Cl, 50mM NaCl, 20% Glycerol, pH8.0.
Molecular Mass: 38.2kDa(including fusion tag)
Protein length: 342aa(including fusion tag)
Applications: WB, ELISA, IP, antibody production, protein array
Storage: Store at -80°C and avoid repeated freeze-thaw cycles.
Gene Name: ATF3 activating transcription factor 3 [ Homo sapiens ]
Official Symbol: ATF3
Synonyms: ATF3; FLJ41705;
Gene ID: 467
mRNA Refseq: NM_001030287
Protein Refseq: NP_001025458
MIM: 603148
UniProt ID: P18847
Chromosome Location: ATF-2 transcription factor network, organism-specific biosystem; Activation of Genes by ATF4, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Disease, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Pathway: identical protein binding; protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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