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Recombinant Human ATG4D, His-tagged

Cat.No. : ATG4D-9977H
Product Overview : Recombinant Human ATG4D protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
Source : E.coli
Species : Human
Tag : His
Protein length : 123-474a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : ATG4D ATG4 autophagy related 4 homolog D (S. cerevisiae) [ Homo sapiens ]
Official Symbol : ATG4D
Synonyms : ATG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); APG4 autophagy 4 homolog D (S. cerevisiae) , APG4D, AUT like 4, cysteine endopeptidase (S. cerevisiae) , AUTL4; cysteine protease ATG4D; APG4 D; autophagin-4; APG4 autophagy 4 homolog D; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; autophagy-related protein 4 homolog D; cysteine protease involved in autophagy; autophagy-related cysteine endopeptidase 4; APG4D; AUTL4; APG4-D;
Gene ID : 84971
mRNA Refseq : NM_032885
Protein Refseq : NP_116274
MIM : 611340
UniProt ID : Q86TL0
Chromosome Location : 19p13.2
Pathway : Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem;
Function : cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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