Recombinant Human ATP10A, His-tagged

• Cat.No.: ATP10A-9995H
• Product Overview: Recombinant Human ATP10A protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1302-1499a.a.
• Description: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene is maternally expressed. It maps within the most common interval of deletion responsible for Angelman syndrome, also known as happy puppet syndrome.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ATP10A ATPase, class V, type 10A [ Homo sapiens ]
• Official Symbol: ATP10A
• Synonyms: ATPase, class V, type 10A; EC 3.6.3.1; ATP10C; ATPase type IV, phospholipid transporting (P-type); ATPVC; phospholipid-transporting ATPase VA; ATPVA; probable phospholipid-transporting ATPase VA; ATPase, Class V, type 10C; ATPase class V type 10A; KIAA0566; EC 3.6.3; Aminophospholipid translocase VA
• Gene ID: 57194
• mRNA Refseq: NM_024490.3
• Protein Refseq: NP_077816.1
• MIM: 605855
• UniProt ID: O60312
• Chromosome Location: 15q11.2
• Pathway: Ion channel transport, organism-specific biosystem; Ion transport by P-type ATPases, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
• Function: ATP binding; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; magnesium ion binding; phospholipid-translocating ATPase activity; protein binding