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Recombinant Human ATP6V1B2 protein, GST-tagged

Cat.No. : ATP6V1B2-1002H
Product Overview : Human ATP6V1B2 full-length ORF ( AAH03100, 1 a.a. - 511 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 81.95 kDa
AA Sequence : MALRAMRGIVNGAAPELPVPTGGPA VGAREQALAVSRNYLSQPRLTYKTV SGVNGPLVILDHVKFPRYAEIVHLT LPDGTKRSGQVLEVSGSKAVVQVFE GTSGIDAKKTSCEFTGDILRTPVSE DMLGRVFNGSGKPIDRGPVVLAEDF LDIMGQPINPQCRIYPEEMIQTGIS AIDGMNSIARGQKIPIFSAAGLPHN EIAAQICRQAGLVKKSKDVVDYSEE NFAIVFAAMGVNMETARFFKSDFEE NGSMDNVCLFLNLANDPTIERIITP RLALTTAEFLAYQCEKHVLVILTDM SSYAEALREVSAAREEVPGRRGFPG YMYTDLATIYERAGRVEGRNGSITQ IPILTMPNDDITHPIPDLTGYITEG QIYVDRQLHNRQIYPPINVLPSLSR LMKSAIGEGMTRKDHADVSNQLYAC YAIGKDVQAMKAVVGEEALTSDDLL YLEFLQKFERNFIAQGPYENRTVFE TLDIGWQLLRIFPKEMLKRIPQSTL SEFYPRDSAKH
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 [ Homo sapiens ]
Official Symbol : ATP6V1B2
Synonyms : ATP6V1B2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; ATP6B2, ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 56/58kD, isoform 2 , ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 2 , VPP3; V-type proton ATPase subunit B, brain isoform; HO57; VATB; Vma2; V-ATPase B2 subunit; V-ATPase subunit B 2; vacuolar proton pump subunit B 2; H+ transporting two-sector ATPase; vacuolar H+-ATPase 56,000 subunit; endomembrane proton pump 58 kDa subunit; VPP3; ATP6B2; ATP6B1B2;
Gene ID : 526
mRNA Refseq : NM_001693
Protein Refseq : NP_001684
MIM : 606939
UniProt ID : P21281

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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