Recombinant Human ATP9B protein, GST-tagged

• Cat.No.: ATP9B-1019H
• Product Overview: Human ATP9B full-length ORF ( AAH53561.1, 1 a.a. - 136 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: ATP9B (ATPase Phospholipid Transporting 9B (Putative)) is a Protein Coding gene. Among its related pathways are Ion channel transport and Cardiac conduction. GO annotations related to this gene include nucleotide binding and cation-transporting ATPase activity. An important paralog of this gene is ATP9A.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 42.7 kDa
• AA Sequence: MPLMMSEEGFENEESDYHTLPRARI MQRKRGLEWFVCDGWKFLCTSCCGW LINICRRKKELKARTVWLGCPEKCE EKHPRNSIKNQKYNVFTFIPGVLYE QFKFFLNLYFLVISCSQFVPALKIG YLYTYWAPLMT
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATP9B ATPase phospholipid transporting 9B (putative) [ Homo sapiens (human) ]
• Official Symbol: ATP9B
• Synonyms: ATP9B; ATPase phospholipid transporting 9B (putative); NEO1L; hMMR1; ATPIIB; ATPASEP; HUSSY-20; probable phospholipid-transporting ATPase IIB; ATPase type IV, phospholipid transporting (P-type); ATPase, class II, type 9B; macrophage MHC receptor 1; EC 3.6.3.1
• Gene ID: 374868
• mRNA Refseq: NM_001306085
• Protein Refseq: NP_001293014
• MIM: 614446
• UniProt ID: O43861

Reviews

03/11/2022

The biological activity of ATP9B is really amazing, and you can see that the purity of the production process is very important, so that you have such a wonderful product.

02/04/2022

Because of its high efficiency and wide applicability, proteins can play their unique advantages in any scientific field.

06/04/2019

Its exceptional stability makes ATP9B a reliable choice for long-term use in various experimental setups.

Q&As

Do ATP9B mutations confer drug resistance?

ATP9B mutations may affect drug transport across the membrane, resulting in the emergence of drug resistance.

Does abnormal ATP9B expression contribute to disease development?

Abnormal ATP9B expression may disturb intracellular ion balance and material transport, thereby affecting cell function and leading to disease development.

Is ATP9B expression regulated by specific environmental factors?

Yes, ATP9B expression levels may be regulated by environmental factors and regulators, such as drugs, physiological states, diseases, etc.

What is the mechanism of action of ATP9B?

ATP9B maintains ion balance and material transport inside and outside the cell by using ATP energy to drive material transport across the membrane.

Does ATP9B transport specific substances inside the cell?

Yes, ATP9B may be involved in the transport of specific substances across the membrane, such as ions, drugs and metabolites.

How to study the function and regulatory mechanism of ATP9B?

The function and regulatory mechanism of ATP9B can be studied using cell culture models, transgenic animal models, and its transport activity can be evaluated in vitro.