Recombinant Human ATXN10, GST-tagged

• Cat.No.: ATXN10-10067H
• Product Overview: Recombinant Human ATXN10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 120-475a.a.
• Description: This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of a pentanucleotide repeat in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ATXN10 ataxin 10 [ Homo sapiens ]
• Official Symbol: ATXN10
• Synonyms: ATXN10; ataxin 10; SCA10, spinocerebellar ataxia 10; ataxin-10; E46L; FLJ37990; brain protein E46 homolog; spinocerebellar ataxia type 10 protein; SCA10; HUMEEP
• Gene ID: 25814
• mRNA Refseq: NM_001167621
• Protein Refseq: NP_001161093
• MIM: 611150
• UniProt ID: Q9UBB4
• Chromosome Location: 22q13
• Function: identical protein binding; protein binding